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The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves
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This article is published in The Journal of Physiology.The article was published on 1910-01-01 and is currently open access. It has received 2435 citations till now. The article focuses on the topics: Dissociation (chemistry).read more
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Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics.
TL;DR: This analysis of resistance evolution finds that pharmacodynamic differences all combine to produce a much lower probability that resistance will evolve against AMPs, and this finding can be generalized to all drugs with pharmacodynamics similar to AMPs.
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Protein corona - from molecular adsorption to physiological complexity.
TL;DR: The relation between particle size and corona composition and the latest findings that help to shed light on temporal evolution of the full serum corona for the first time are addressed.
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Application of the kinetic and isotherm models for better understanding of the behaviors of silver nanoparticles adsorption onto different adsorbents.
TL;DR: Assessment of the reliability and validity of thirty kinetic and isotherm models for describing the behaviors of adsorption of silver nanoparticles (AgNPs) onto different adsorbents finds fractal-like mixed 1, 2-order model and Fritz-Schlunder and Baudu models can be recommended as the most reliable models for AgNPs adorption onto the natural and synthetic adsorbent materials.
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Changes in myofibrillar activation and troponin C Ca2+ binding associated with troponin T isoform switching in developing rabbit heart.
TL;DR: The data indicate that the Ca2+ activation andCa2+ binding properties of myofibrillar troponin C are altered in developing cardiac myofibils and that the changes in these properties may be influenced by changes in the Troponin T isoforms present in the my ofibril.
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Determination of microscopic acid–base parameters from NMR–pH titrations
TL;DR: The theory and practice of proton microspeciation based on NMR–pH titrations are surveyed and literature data on complete microspeciations of small ligands and site-specific basicity characterizations of peptides and proteins are critically reviewed.