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The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure
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This article is published in JAMA Internal Medicine.The article was published on 1997-01-01 and is currently open access. It has received 5537 citations till now.read more
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Second manifestations of ARTerial disease (SMART) study: rationale and design.
TL;DR: The Second Manifestations of ARTerial disease (SMART) study is a single-centre prospective cohort study among patients, newly referred to the hospital with clinically manifest atherosclerotic vessel disease, or marked risk factors for atherosclerosis to determine the prevalence of concomitant arterial disease at other sites, and risk factors in patients presenting with a manifestation of arterials disease or vascular risk factor.
Journal ArticleDOI
Impact of Diabetes on Cardiovascular Disease: An Update
Alessandra S. M. Matheus,Lucianne Righeti Monteiro Tannus,Roberta Arnoldi Cobas,Cátia Cristina Silva Sousa Vergara Palma,Carlos Antonio Negrato,Marília B. Gomes +5 more
TL;DR: The association between poor glycemic control, oxidative stress, markers of insulin resistance, and of low-grade inflammation that have been suggested as putative factors linking diabetes and cardiovascular disease are described.
Journal ArticleDOI
Serum Carboxy-Terminal Propeptide of Procollagen Type I Is a Marker of Myocardial Fibrosis in Hypertensive Heart Disease
Ramón Querejeta,Nerea Varo,Begoña López,Mariano Larman,Edurne Artiñano,J.C. Etayo,José L. Martínez Ubago,Marian Gutierrez-Stampa,José I. Emparanza,María J. Gil,Ignacio Monreal,Javier Pardo Mindán,Javier Díez +12 more
TL;DR: Findings suggest that the determination of PIP may be an easy and reliable method for the screening and diagnosis of severe myocardial fibrosis associated with arterial hypertension.
Journal ArticleDOI
Insulin Resistance as an Independent Predictor of Cardiovascular Mortality in Patients with End-Stage Renal Disease
Kayo Shinohara,Tetsuo Shoji,Masanori Emoto,Hideki Tahara,Hidenori Koyama,Eiji Ishimura,Takami Miki,Tsutomu Tabata,Yoshiki Nishizawa +8 more
TL;DR: It is indicated that insulin resistance is an independent predictor of cardiovascular mortality in ESRD and the effect of HOMA-IR on cardiovascular mortality was independent of body mass index, hypertension, and dyslipidemia.
Journal ArticleDOI
Independent and Additive Impact of Blood Pressure Control and Angiotensin II Receptor Blockade on Renal Outcomes in the Irbesartan Diabetic Nephropathy Trial: Clinical Implications and Limitations
Marc A. Pohl,Samuel S. Blumenthal,D. Cordonnier,Fernando De Alvaro,Giacomo Deferrari,Gilbert M. Eisner,Enric Esmatjes,Richard E. Gilbert,Lawrence G. Hunsicker,José B. Lopes de Faria,Ruggero Mangili,Jack Moore,Efrain Reisin,Eberhard Ritz,Guntram Schernthaner,Samuel Spitalewitz,Hilary Tindall,Roger A. Rodby,Edmund J. Lewis +18 more
TL;DR: A SBP target between 120 and 130 mmHg is recommended, in conjunction with blockade of the renin-angiotensin system, in patients with type 2 diabetic nephropathy, and Progressive lowering of SBP to 120mmHg was associated with improved renal and patient survival, an effect independent of baseline renal function.
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