Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
Citations
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A Hybrid Deep Learning and Handcrafted Features based Approach for Thyroid Nodule Classification in Ultrasound Images
Journal ArticleDOI
Current status of biomarker testing in historically rare, high-unmet-need tumors: soft tissue sarcomas and thyroid cancers.
Bridgette Schroader,Sheldon Kong,Sibyl Anderson,Todd Williamson,Anthony Sireci,Kasia Shields +5 more
TL;DR: A gap exists between guideline recommendations for biomarker testing and clinical application, resulting in compromised access and suboptimal outcomes, and future progress will require routine access to testing and expanding treatment options coupled with awareness, predictability, and strategies to address resistance mechanisms.
Journal ArticleDOI
Physician Confidence in Neck Ultrasonography for Surveillance of Differentiated Thyroid Cancer Recurrence.
Kevin J. Kovatch,David Reyes-Gastelum,Jennifer A. Sipos,Elaine M. Caoili,Ann S. Hamilton,Kevin C. Ward,Megan R. Haymart +6 more
TL;DR: In this article, the authors evaluated physicians' post-treatment surveillance practices for DTC recurrence, specifically their use of and confidence in ultrasonography. And they found that physicians' low confidence in their own ability and that of radiologists to use ultrasonograph to detect recurrence point to a major obstacle to standardizing long-term DTC surveillance practices.
Journal ArticleDOI
Exploring physicians and patients' perspectives for current interventions on thyroid nodules using a MCDA method
TL;DR: In this article, an online survey was developed using a comprehensive multi-criteria decision analysis (MCDA) framework, the EVIdence based decision-making (EVIDEM), to explore physicians' and patients' insights and preferences regarding the current interventions on thyroid nodules.
Journal ArticleDOI
The Controversial Role of Vitamin D in Thyroid Cancer Prevention
TL;DR: Data provide evidence that circulating vitamin D concentration is inversely correlated with disease aggressiveness and poor prognosis, while evidence of an association with tumour initiation remains weak, and a variety of data support an anti-tumorigenic role of vitamin D and its potential utility as a secondary chemopreventive agent.
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