Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
Citations
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PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports
Maike J. M. Uijen,Yvonne H.W. Derks,R I J Merkx,Melline G.M. Schilham,Joey Roosen,Bastiaan M. Privé,S van Lith,C.M.L. van Herpen,Martin Gotthardt,Sandra Heskamp,W A M van Gemert,James Nagarajah +11 more
TL;DR: In this paper, the authors describe the current knowledge of PSMA expression in other solid cancers and define a perspective towards broader clinical implementation of prostate-specific membrane antigen (PSMA)-RLT.
Journal ArticleDOI
Time trends and age-period-cohort analyses on incidence rates of thyroid cancer in Shanghai and Hong Kong
Shao-Hua Xie,Juan Chen,Bo Zhang,Bo Zhang,Feng Wang,Shan-Shan Li,Chang-Hui Xie,Lap Ah Tse,Jin-Quan Cheng +8 more
TL;DR: The increased incidence rates of thyroid cancer in these two Chinese populations during recent decades may be contributable to a combination of the introduction of more sensitive diagnostic techniques and the increasing prevalence of environmental exposures in the populations.
Journal ArticleDOI
Deep learning based classification of ultrasound images for thyroid nodules: a large scale of pilot study.
TL;DR: Nodules that are 0.5-1.0 cm in size and have microcalcification and a taller shape can be more accurately diagnosed by Inception-v3, and can achieve an excellent diagnostic efficiency.
Journal ArticleDOI
Thyroid cytology—nuclear versus architectural atypia within the “Atypia of undetermined significance/follicular lesion of undetermined significance” Bethesda category have significantly different rates of malignancy
Tiffany Rui Xuan Gan,Min En Nga,Jeffrey Huey Yew Lum,Wendy Meihua Wong,Wee Boon Tan,Rajeev Parameswaran,Kee Yuan Ngiam +6 more
TL;DR: The objectives of this study were to describe the differential malignancies rates of FNACs diagnosed as AUS/FLUS based on nuclear or architectural atypia and to assess the significance of demographic and ultrasonographic features in predicting malignancy in this category.
Journal ArticleDOI
Long-Term Declines of Thyroid Cancer Mortality: An International Age-Period-Cohort Analysis
TL;DR: Global long-term declines in TC mortality have been accompanied by downward trends in both period and cohort effects, and indirectly confirm the main role of overdiagnosis in the epidemic of TC incidence.
References
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