Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
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Incidental versus clinically diagnosed differentiated thyroid cancer in both adult and elderly subjects: histological characteristics and follow-up in a retrospective analysis from a single institution
TL;DR: In this paper, the authors retrospectively analyzed data from 440 patients consecutively diagnosed with differentiated thyroid cancer (DTC) in a single institution and categorized the diagnosis modalities as clinically diagnosed, non-incidental cases, incidental during carotid power-duplex (CPD), incidental during neck imaging other than CPD; incidental during imaging workup of thyroid dysfunction or at histological examination after thyroidectomy for benign lesions.
Journal Article
What Do Korean Women Know and Want to Know about Thyroid Cancer? A Qualitative Study
Bomyee Lee,Jae Young Park,Hye Young Shin,Sang Hee Park,Eun-Bi Choi,Jisu Yoo,Kui Son Choi,Jae Kwan Jun +7 more
TL;DR: A widespread lack of awareness of information on thyroid cancer was noted among participants in groups 1 and 2 who were not well aware of thyroid cancer and generally recognized it as a'good cancer'.
Journal ArticleDOI
Long Non-coding RNA RUNDC3A-AS1 Promotes Lung Metastasis of Thyroid Cancer via Targeting the miR-182-5p/ADAM9.
Dawei Ma,Yan Zhu,Xiao Zhang,Jia Zhang,Wei Chen,Xinyuan Chen,Yichun Qian,Yanbin Zhao,Tingting Hu,Zhangyu Yao,Wei Zhao,Yuan Zhang,Fangzhou Liu +12 more
TL;DR: In this article, the authors examined the expression levels of RunDC3A-AS1 in the thyroid cancer tissues and cell lines via RT-qPCR analysis and found that rundc3a-as1 was highly expressed in thyroid cells and was an inhibitor of miR-182-5p.
Time trends and age-period-cohort analyses on incidence rates of thyroid cancer in Shanghai
Shao-Hua Xie,Juan Chen,Bo Zhang,Feng Wang,Shan-Shan Li,Chang-Hui Xie,Lap-Ah Tse,Jin-Quan Cheng +7 more
TL;DR: The increased incidence rates of thyroid cancer in these two Chinese populations during recent decades may be contributable to a combination of the introduction of more sensitive diagnostic techniques and the increasing prevalence of environmental exposures in the populations.
References
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Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
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