Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
Citations
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Usefulness of albumin-globulin ratio as a clinical prognostic factor in patients with thyroid cancer treated with radioiodine.
Noriko Takata,Masao Miyagawa,Takuya Matsuda,Masahiro Takakado,Tomohisa Okada,Naoto Kawaguchi,Kenji Makita,Hirofumi Ishikawa,Shintaro Tsuruoka,K. Uwatsu,Teruhito Kido +10 more
TL;DR: In this article, the authors reveal the relationship between albumin-globulin ratio (AGR) and overall survival (OS) in patients with thyroid cancer who received radioactive iodine therapy (RIT).
Journal ArticleDOI
Etiopathogenesis of Differentiated Thyroid Carcinomas
TL;DR: This new molecular insight could have a crucial impact on diagnosis and also on improving and selecting an appropriate treatment to the patients with thyroid malignancies.
Journal ArticleDOI
BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinoma
Xing Chen,Shan Hu Lin,Ying Lin,Songsong Wu,Min ling Zhuo,Ailong Zhang,Jun-yi Zheng,Zhenhui You +7 more
TL;DR: In this paper , a comprehensive bioinformatics analysis was performed to identify the differentially expressed genes and signaling pathways in thyroid cancer patients carrying mutant BRAF and confirmed the prognostic role of WT1 in thyroid Cancer patients.
Journal ArticleDOI
Clinical significance of miR-34a expression in thyroid diseases - an 18 F-FDG PET-CT study
Long Chen,Yang Conghui,Feng Jun,Xin Liu,Yadong Tian,Lei Zhao,Ran Xie,Chao Liu,Zhao Sheng,Sun Hua +9 more
TL;DR: In this article, the miR-34a expression was found to be upregulated in thyroid lesions, negatively correlated with SUVmax and can be predicted by FDG SUVmax.
Journal ArticleDOI
Anticancer effects of natural phytochemicals in anaplastic thyroid cancer
TL;DR: Findings in this review enrich the knowledge of the anticancer effects of phytochemicals and highlight alternative therapies to prevent drug resistance in anaplastic thyroid cancer.
References
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Journal ArticleDOI
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.
TL;DR: The results for 20 world regions are presented, summarizing the global patterns for the eight most common cancers, and striking differences in the patterns of cancer from region to region are observed.
Journal ArticleDOI
Cancer statistics, 2014
TL;DR: The magnitude of the decline in cancer death rates from 1991 to 2010 varies substantially by age, race, and sex, ranging from no decline among white women aged 80 years and older to a 55% decline among black men aged 40 years to 49 years.
Journal ArticleDOI
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib,Benjamin Smith,Rhonda Aizenberg,Allison B. Rosenzweig,Julie M. Fleshman,Lynn M. Matrisian +5 more
TL;DR: Pancreas and liver cancers are projected to surpass breast, prostate, and colorectal cancers to become the second and third leading causes of cancer-related death by 2030, respectively.
Book
The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today
Richard Doll,Richard Peto +1 more
TL;DR: Evidence that the various common types of cancer are largely avoidable diseases is reviewed, and it is suggested that, apart from cancer of the respiratory tract, the types of cancers that are currently common are not peculiarly modern diseases and are likely to depend chiefly on some long-established factor.
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