Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
Citations
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Journal ArticleDOI
Increase in Papillary Thyroid Cancer Incidence Is Accompanied by Changes in the Frequency of the BRAFV600E Mutation: A Single-Institution Study
Aldona Kowalska,Agnieszka Walczyk,Artur Kowalik,Iwona Pałyga,Tomasz Trybek,Janusz Kopczyński,Maciej Kajor,Magdalena Chrapek,Liliana Pięciak,Małgorzata Chłopek,Stanisław Góźdź,Grzegorz Kamiński +11 more
TL;DR: The prevalence of the BRAF(V600E) mutation increased significantly in PTCs diagnosed at a single institution over 14 years in Poland, a country with a demonstrated improvement in iodine supplementation in the early 21st century.
Journal ArticleDOI
Thyroid cancer invading the airway: diagnosis and management.
Nicola Avenia,Jacopo Vannucci,Massimo Monacelli,Roberta Lucchini,Andrea Polistena,Stefano Santoprete,Rossella Potenza,Marco Andolfi,Francesco Puma +8 more
TL;DR: Although some patients are currently referred with a severely advanced disease, the indication for tracheotomy, salvage procedures or supportive care has decreased over time and Resection is feasible for differentiated tumors with an overall good outcome.
Journal ArticleDOI
CircNUP214 sponges miR-145 to promote the expression of ZEB2 in thyroid cancer cells.
TL;DR: Evidence is found that circNUP214 was upregulated in clinical PTC specimens relative to adjacent normal tissue, providing evidence for a new regulatory mechanism in PTC development involving circNup214, which can serve as a potential therapeutic target in P TC treatment.
Journal ArticleDOI
Nationwide cohort study on the epidemiology and survival outcomes of thyroid cancer
Fu-Chao Liu,Fu-Chao Liu,Huan-Tang Lin,Huan-Tang Lin,Shu-Fu Lin,Chang-Fu Kuo,Chang-Fu Kuo,Ting-Ting Chung,Huang-Ping Yu,Huang-Ping Yu +9 more
TL;DR: Thyroid cancer was more prevalent in patients with high socioeconomic status and in urban areas and the overall survival rates by sex and subtype remained stable over time, with 5-year survival rates of 90.2% in 1997 and 92.4% in 2010.
Journal ArticleDOI
A review of incidence and mortality of colorectal, lung, liver, thyroid, and bladder cancers in Iran and compared to other countries.
TL;DR: In this review, incidence and mortality of colorectal, lung, liver, thyroid, and bladder cancers in Iran are reported and it is recommended that the high-risk population receive earlier screening.
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