Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
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Cancer patterns and trends in Central and South America
Mónica S. Sierra,Isabelle Soerjomataram,Sebastien Antoni,Mathieu Laversanne,Marion Piñeros,Esther de Vries,David Forman +6 more
TL;DR: CSA carries a double-burden of cancer, with elevated rates of infection- and lifestyle-related cancers and an overwhelming need to improve the quality and coverage of cancer registration to guide and evaluate future cancer control policies and programs.
Journal ArticleDOI
Sesame Inhibits Cell Proliferation and Induces Apoptosis through Inhibition of STAT-3 Translocation in Thyroid Cancer Cell Lines (FTC-133)
Yunhai Ma,Thiruventhan Karunakaran,Vishnu Priya Veeraraghavan,Surapaneni Krishna Mohan,Shuling Li +4 more
TL;DR: It is established that sesame deactivates STAT-3 translocation, thereby reducing the elevated expression of, cyclin-D1, Bcl-2 and diminished expression of Bax, caspase-9 and 3 in FTC-133 cell lines.
Journal ArticleDOI
Follicular cell-derived thyroid cancer
Henning Dralle,Andreas Machens,Johanna Basa,Vahab Fatourechi,Silvia Franceschi,Ian D. Hay,Yuri E. Nikiforov,Furio Pacini,Janice L. Pasieka,Steven I. Sherman +9 more
TL;DR: Improvement in the health-related quality of life of survivors of follicular cell-derived thyroid cancer, which is decreased despite the generally favourable outcome, hinges on early tumour detection and minimization of treatment-related sequelae.
Journal ArticleDOI
Prognostic value of the eighth edition AJCC TNM classification for differentiated thyroid carcinoma.
Tae Hyuk Kim,Young Nam Kim,Hye In Kim,So-Young Park,Jun-Ho Choe,Jung-Han Kim,Jee Soo Kim,Young Lyun Oh,Soo Yeon Hahn,Jung Hee Shin,Kyunga Kim,Jong Gill Jeong,Sun Wook Kim,Jae Hoon Chung +13 more
TL;DR: The results demonstrate that the eighth edition TNM more accurately predicts cancer-specific survival for patients with DTC than does the seventh edition.
Journal ArticleDOI
Thyroid cancer “epidemic” also occurs in low‐ and middle‐income countries
TL;DR: The very high thyroid cancer incidence and low mortality rates in some LMICs also strongly suggest a major role of overdiagnosis in these countries.
References
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