Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
Citations
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Journal ArticleDOI
2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS.
JianQiao Zhou,LiXue Yin,Xi Wei,Sheng Zhang,YanYan Song,Baoming Luo,Jianchu Li,Linxue Qian,Li-Gang Cui,Wen Chen,Chaoyang Wen,Yu-Lan Peng,Qin Chen,Man Lu,Min Chen,Rong Wu,Wei Zhou,En-Sheng Xue,Ying-Jia Li,LiChun Yang,ChengRong Mi,RuiFang Zhang,Gang Wu,Guoqing Du,DaoZhong Huang,Weiwei Zhan,Superficial Organ,Breast Ultrasound +27 more
TL;DR: The Chinese-TIRADS that is in line with China’s national conditions and medical status was established based on literature review, expert consensus, and multicenter data provided by the Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound.
Journal ArticleDOI
Development of a prognostic index based on an immunogenomic landscape analysis of papillary thyroid cancer
Peng Lin,Yi-Nan Guo,Lin Shi,Xiao-jiao Li,Hong Yang,Yun He,Qing Li,Yi-Wu Dang,Kang-Lai Wei,Gang Chen +9 more
TL;DR: Together, the results screened several IRGs of clinical significance, revealed drivers of the immune repertoire, and demonstrated the importance of a personalized, IRG-based immune signature in the recognition, surveillance, and prognosis of PTC.
Journal ArticleDOI
The epidemiological landscape of thyroid cancer worldwide: GLOBOCAN estimates for incidence and mortality rates in 2020.
Margherita Pizzato,Mengmeng Li,Jérôme Vignat,Mathieu Laversanne,Deep M. Singh,Carlo La Vecchia,Salvatore Vaccarella +6 more
TL;DR: In this paper , the authors provided an up-to-date assessment on the global distribution of thyroid cancer incidence and mortality rates in 2020, using the GLOBOCAN database.
Journal ArticleDOI
Growing incidence of thyroid carcinoma in recent years: Factors underlying overdiagnosis
Alvaro Sanabria,Luiz Paulo Kowalski,Jatin P. Shah,Iain J. Nixon,Peter Angelos,Michelle D. Williams,Alessandra Rinaldo,Alfio Ferlito +7 more
TL;DR: The factors that contribute to the increasing incidence are addressed and environmental, and patient‐based and clinician‐led influences are considered, resulting in a significant phenomenon of overdiagnosis.
Journal ArticleDOI
Microarray profiling of circular RNAs in human papillary thyroid carcinoma.
TL;DR: Several promising cancer-related genes may be targets of the dysregulated hsa_circRNA_100395/miR-141-3p/ miR-200a- 3p axis in PTC tumors.
References
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The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today
Richard Doll,Richard Peto +1 more
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