Journal ArticleDOI
Thyroid cancer mortality and incidence: A global overview
Carlo La Vecchia,Matteo Malvezzi,Cristina Bosetti,Werner Garavello,Paola Bertuccio,Fabio Levi,Eva Negri +6 more
TLDR
The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.Abstract:
In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970-2012) and incidence data from the Cancer Incidence in Five Continents (1960-2007). Male mortality declined in all the major countries considered, with annual percent changes around -2/-3% over the last decades. Only in the United States mortality declined up to the mid 1980s and increased thereafter. Similarly, in women mortality declined in most countries considered, with APCs around -2/-5% over the last decades, with the exception of the UK, the United States and Australia, where mortality has been declining up to the late 1980s/late 1990s to level off (or increase) thereafter. In 2008-2012, most countries had mortality rates (age-standardized, world population) between 0.20 and 0.40/100,000 men and 0.20 and 0.60/100,000 women, the highest rates being in Latvia, Hungary, the Republic of Moldova and Israel (over 0.40/100,000) for men and in Ecuador, Colombia and Israel (over 0.60/100,000) for women. In most countries, a steady increase in the incidence of thyroid cancer (mainly papillary carcinomas) was observed in both sexes. The declines in thyroid cancer mortality reflect both variations in risk factor exposure and changes in the diagnosis and treatment of the disease, while the increases in the incidence are likely due to the increase in the detection of this neoplasm over the last few decades.read more
Citations
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Journal ArticleDOI
Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis
Salvatore Vaccarella,Silvia Franceschi,Freddie Bray,Christopher P. Wild,Martyn Plummer,Luigino Dal Maso +5 more
TL;DR: There are concerns that hundreds of thousands of cases may be overdiagnoses — diagnosis of tumors that would not, if left alone, result in symptoms or death.
Journal ArticleDOI
The Impact of Diagnostic Changes on the Rise in Thyroid Cancer Incidence: A Population-Based Study in Selected High-Resource Countries.
Salvatore Vaccarella,Luigino Dal Maso,Mathieu Laversanne,Freddie Bray,Martyn Plummer,Silvia Franceschi +5 more
TL;DR: A large proportion of TC cases diagnosed in high-resource countries in the last two decades are likely to be due to diagnostic changes, and this proportion has progressively increased over time, and it is likely to grow further in the future.
Journal ArticleDOI
Evolving Understanding of the Epidemiology of Thyroid Cancer.
Carolyn D. Seib,Julie Ann Sosa +1 more
TL;DR: The incidence of thyroid cancer worldwide has increased significantly over the past 3 decades, due predominantly to an increase in papillary thyroid cancer, but there also appears to be a true increase in new cases.
Journal ArticleDOI
Geographic influences in the global rise of thyroid cancer.
TL;DR: This Review highlights the epidemiology of thyroid cancer in high-income, middle-income and low-income countries and discusses the prevalence of modifiable individual risk factors and population-level exposures to environmental risk factors.
Journal ArticleDOI
Iodine intake as a risk factor for thyroid cancer: a comprehensive review of animal and human studies
TL;DR: The available evidence suggests iodine deficiency is a risk factor for TC, particularly for follicular TC and possibly, for anaplastic TC.
References
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Journal ArticleDOI
Increasing incidence of thyroid cancer in the United States, 1973-2002.
Louise Davies,H. Gilbert Welch +1 more
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Overdiagnosis in Cancer
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Thyroid Cancer after Exposure to External Radiation: A Pooled Analysis of Seven Studies
Elaine Ron,Jay H. Lubin,Roy E. Shore,Kiyohiko Mabuchi,Baruch Modan,Linda M. Pottern,Arthur B. Schneider,Margaret A. Tucker,John D. Boice +8 more
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Related Papers (5)
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013.
Increasing incidence of thyroid cancer in the United States, 1973-2002.
Louise Davies,H. Gilbert Welch +1 more