Journal ArticleDOI
Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health.
Jing Zhang,Kaili Hu,Liuqing Di,Penglong Wang,Zhidong Liu,Jinming Zhang,Pengfei Yue,Wantong Song,Jingwei Zhang,Tongkai Chen,Zuhua Wang,Yongtai Zhang,Xiaoying Wang,Changyou Zhan,Yung-Chi Cheng,Xiang Li,Quan Li,Jing-Yu Fan,Youqing Shen,Jing-Yan Han,Hongzhi Qiao +20 more
TLDR
In this article, the authors discuss the overlapping connectivity and relevance of the two fields, including nanoaggregates generated in herbal medicine decoctions, the application of nanotechnology in the delivery and treatment of natural active ingredients, and the influence of physiological regulatory capability of traditional herbal medicine on the in vivo fate of nanoparticles.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2021-09-06. It has received 37 citations till now.read more
Citations
More filters
Journal ArticleDOI
Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology.
TL;DR: In this paper , the structure-activity relationship of epimedium flavonoids is described and enzymatic engineering strategies for increasing the productivity of highly active baohuoside I and icaritin are discussed.
Journal ArticleDOI
Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review
TL;DR: A comprehensive summary of the research status and application prospect of nano-delivery strategies for the combination of natural active ingredients and chemotherapy drugs, aiming to provide a basis for the development of anti-tumor drugs.
Journal ArticleDOI
Green synthesis of nanoparticles for varied applications: Green renewable resources and energy-efficient synthetic routes
Mohamed Madani,Shimaa Hosny,Dalal Mohamed Alshangiti,Norhan Nady,Sheikha A. Alkhursani,Huda Alkhaldi,S.A. Al-Gahtany,Mohamed Mohamady Ghobashy,Ghalia A. Gaber +8 more
TL;DR: In this paper , the authors present an outline of the 12 principles of green relevance in nanomaterial synthesis and show how different green renewable resources routes are reducing the impact of chemical processes on the environment and how their benefit can be achieved in nanotechnology applications.
Journal ArticleDOI
Research progress on self-assembled nanodrug delivery systems.
TL;DR: The research progress and applications of different types of self-assembled nanodrug delivery systems are summarized, which are expected to have potential therapeutic value in the field of biomedicine in the future.
Journal ArticleDOI
Anti-Parkinsonian Therapy: Strategies for Crossing the Blood–Brain Barrier and Nano-Biological Effects of Nanomaterials
Guowang Cheng,Yujing Liu,Rui Ma,Guopan Cheng,Yucheng Guan,Xiao-jun Chen,Zhen Wu,Tongkai Chen +7 more
TL;DR: In this article , the authors discuss the clinical value of nanotechnology in Parkinson's disease treatment based on recent patents and could guide researchers working in this area in the future, and highlight the emerging strategies for crossing the BBB and the development of novel nanomaterials with anti-PD nano-biological effects.
References
More filters
Journal Article
A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
Yasuhiro Matsumura,Hiroshi Maeda +1 more
TL;DR: It is speculated that the tumoritropic accumulation of smancs and other proteins resulted because of the hypervasculature, an enhanced permeability to even macromolecules, and little recovery through either blood vessels or lymphatic vessels in tumors of tumor-bearing mice.
Journal ArticleDOI
A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
TL;DR: A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is proposed based on recognizing that drug dissolution and gastrointestinal permeability are the fundamental parameters controlling rate and extent of drug absorption.
Journal ArticleDOI
Hypoxia — a key regulatory factor in tumour growth
TL;DR: Cells undergo a variety of biological responses when placed in hypoxic conditions, including activation of signalling pathways that regulate proliferation, angiogenesis and death, and many elements of the hypoxia-response pathway are good candidates for therapeutic targeting.
Journal ArticleDOI
Principles of nanoparticle design for overcoming biological barriers to drug delivery
TL;DR: By successively addressing each of the biological barriers that a particle encounters upon intravenous administration, innovative design features can be rationally incorporated that will create a new generation of nanotherapeutics, realizing a paradigmatic shift in nanoparticle-based drug delivery.
Journal ArticleDOI
Shedding light on the cell biology of extracellular vesicles.
TL;DR: Extracellular vesicles are now considered as an additional mechanism for intercellular communication, allowing cells to exchange proteins, lipids and genetic material.
Related Papers (5)
Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions
Thomas J. Anchordoquy,Yechezkel Barenholz,Diana Boraschi,Michael Chorny,Paolo Decuzzi,Marina A. Dobrovolskaia,Z. Shadi Farhangrazi,Dorothy Farrell,Alberto Gabizon,Hamidreza Ghandehari,Biana Godin,Ninh M. La-Beck,Julia Y. Ljubimova,S. Moein Moghimi,Len Pagliaro,Ji-Ho Park,Dan Peer,Erkki Ruoslahti,Natalie J. Serkova,Dmitri Simberg +19 more