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Open AccessJournal ArticleDOI

The big picture on nanomedicine: the state of investigational and approved nanomedicine products

TLDR
The state of nanomedicine commercialization is discussed, concentrating only on nanomediine-based developments and products that are either in clinical trials or have already been approved for use.
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This article is published in Nanomedicine: Nanotechnology, Biology and Medicine.The article was published on 2013-01-01 and is currently open access. It has received 858 citations till now. The article focuses on the topics: Modern medicine.

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Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date.

TL;DR: An up to date snapshot of nanomedicines either currently approved by the US FDA, or in the FDA clinical trials process is provided, and there is a trend towards the development of more complex materials comprising micelles, protein-based NPs, and also the emergence of a variety of inorganic and metallic particles in clinical trials.
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Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

TL;DR: This review extensively discusses the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral,Anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti- cancer activity of Ag NPs.
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Liposomes as nanomedical devices

TL;DR: This review briefly analyze how the efficacy of liposomes depends on the nature of their components and their size, surface charge, and lipidic organization, and describes some strategies developed to overcome limitations of the “first-generation” liposome-based drugs on the market and in clinical trials.
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Nanoparticle Uptake: The Phagocyte Problem.

TL;DR: This review focuses on describing macrophage-based initiation of downstream hallmark immunological and inflammatory processes resulting from phagocyte exposure to and internalization of nanomaterials.
References
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Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.

TL;DR: A review of gold nanoparticles can be found in this article, where the most stable metal nanoparticles, called gold colloids (AuNPs), have been used for catalysis and biology applications.
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High-performance lithium battery anodes using silicon nanowires

TL;DR: The theoretical charge capacity for silicon nanowire battery electrodes is achieved and maintained a discharge capacity close to 75% of this maximum, with little fading during cycling.
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Nanowire dye-sensitized solar cells

TL;DR: This work introduces a version of the dye-sensitized cell in which the traditional nanoparticle film is replaced by a dense array of oriented, crystalline ZnO nanowires, which features a surface area up to one-fifth as large as a nanoparticle cell.
Journal ArticleDOI

Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.

TL;DR: The intracellular uptake of different sized and shaped colloidal gold nanoparticles is investigated and it is shown that kinetics and saturation concentrations are highly dependent upon the physical dimensions of the nanoparticles.
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