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Journal ArticleDOI

Ultrasonic Mixing in Microfluidic Channels Using Integrated Transducers

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TLDR
A microfluidic mixer that uses acoustic stirring created by ultrasonic waves to mix phenolphthalein solution and sodium hydroxide dissolved in ethyl alcohol is presented.
Abstract
This paper presents a microfluidic mixer that uses acoustic stirring created by ultrasonic waves. The ultrasound is introduced into the channel by integrated piezoelectric transducers. The transducers are made of a zinc oxide thin film, which is deposited on the bottom surface of a quartz substrate. The poly(dimethylsiloxane) channel is aligned to the transducers on the top surface of the substrate. The transducers are designed for operation around 450 MHz. The main mechanism of the mixing is the acoustic stirring of the fluid perpendicular to the flow direction. The radiation pressure that is generated by the transducer causes the stirring inside the microfluidic channel. The performance of the mixer is characterized by mixing phenolphthalein solution and sodium hydroxide dissolved in ethyl alcohol. Flow rates on the order of 1−100 μL/min are used. The transducers are driven by 1.2 Vrms sinusoidal voltages at 450 MHz.

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References
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Journal ArticleDOI

Chaotic mixing in three-dimensional microvascular networks fabricated by direct-write assembly

TL;DR: It is envisaged that 3D microvascular networks will provide an enabling platform for a wide array of fluidic-based applications.
Journal ArticleDOI

Ultrasonic micromixer for microfluidic systems

TL;DR: In this paper, an active micromixer for continuous flow is described, where the flow path is encapsulated by anodic bonding of a Si wafer to the glass and a diaphragm is etched on the Si side to prevent ultrasonic radiation from escaping to the other parts of the device.
Journal ArticleDOI

Chaotic advection by laminar flow in a twisted pipe

TL;DR: In this article, the appearance of chaotic particle trajectories in steady, laminar, incompressible flow through a twisted pipe of circular cross-section is demonstrated using standard dynamical systems diagnostics and a model flow based on Dean's perturbation solutions.
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A modular microfluid system with an integrated micromixer

TL;DR: In this paper, a static micromixer built up in silicon wafers is described, where the structured surfaces are bonded together by using a low temperature silicon direct bonding process.
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