Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance
Norah A. Terrault,Anna S. Lok,Brian J. McMahon,Kyong-Mi Chang,Jessica P. Hwang,Maureen M. Jonas,Robert S. Brown,Natalie Bzowej,John B. Wong +8 more
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TLDR
This AASLD 2018 Hepatitis B Guidance provides a data-supported approach to screening, prevention, diagnosis, and clinical management of patients with hepatitis B.About:
This article is published in Hepatology.The article was published on 2018-04-01 and is currently open access. It has received 2399 citations till now. The article focuses on the topics: Hepatitis B & Mass screening.read more
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Increasing antiviral treatment uptake improves survival in patients with HBV-related HCC
Vicki Wing-Ki Hui,Stephen L. Chan,Vincent Wai-Sun Wong,Lilian Yan Liang,Terry Cheuk-Fung Yip,Jimmy Che-To Lai,Becky Wing-Yan Yuen,Hester Wing-Sum Luk,Yee-Kit Tse,Hye Won Lee,Henry Lik-Yuen Chan,Grace Lai-Hung Wong +11 more
TL;DR: The uptake of antiviral treatment in HCC patients increased over the past decade and it is never too late to initiate NA treatment, even after HCC diagnosis, which contributed mostly to the uptake rate.
Journal ArticleDOI
Single Hepatocyte Hepatitis B Virus Transcriptional Landscape in HIV Coinfection.
Ashwin Balagopal,Hyon S. Hwang,Tanner Grudda,Jeffrey Quinn,Richard K. Sterling,Mark S. Sulkowski,Chloe L. Thio +6 more
TL;DR: It is concluded that cccDNA transcription is reduced in HIV/HBV co-infected people with longer antiviral duration, which may be critical to develop a functional cure.
Journal ArticleDOI
Prevention and management of viral hepatitis in inflammatory bowel disease: a clinical practice guideline by the Korean Association for the Study of Intestinal Diseases.
Soo-Kyung Park,Chang Hwan Choi,Jaeyoung Chun,Heeyoung Lee,Eun Sun Kim,Jae Jun Park,Chan Hyuk Park,Bo-In Lee,Yunho Jung,Dong Il Park,Do Young Kim,Hana Park,Yoon Tae Jeen +12 more
TL;DR: Members of IBD research group of the Korean Association for the Study of Intestinal Diseases have produced a guideline on the prevention and management of viral hepatitis in IBD.
Journal ArticleDOI
Risks and Benefits of Discontinuation of Nucleos(t)ide Analogue Treatment: A Treatment Concept for Patients With HBeAg-Negative Chronic Hepatitis B.
Florian van Bömmel,Thomas Berg +1 more
TL;DR: For selected patients, NA discontinuation has become a powerful tool to achieve control over HBeAg‐negative HBV infections and represents a challenge to novel treatment approaches, but it may also serve as their enhancer.
Journal ArticleDOI
Baseline Mac-2 Binding Protein Glycosylation Isomer Level Stratifies Risks of Hepatocellular Carcinoma in Chronic Hepatitis B Patients with Oral Antiviral Therapy.
Tai-Chung Tseng,Cheng Yuan Peng,Yao-Chun Hsu,Tung-Hung Su,Chia-Chi Wang,Chun-Jen Liu,Hung-Chih Yang,Wan-Ting Yang,Chia Hsin Lin,Ming-Lung Yu,Hsueh Chou Lai,Yasuhito Tanaka,Mindie H. Nguyen,Chen-Hua Liu,Pei-Jer Chen,Ding-Shinn Chen,Jia-Horng Kao +16 more
TL;DR: In CHB patients receiving long-term antiviral treatment, serum M2BPGi level not only serves as an independent HCC predictor but also complements PAGE-B in stratifying HCC risks.
References
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Management of hepatocellular carcinoma.
Jordi Bruix,Morris Sherman +1 more
TL;DR: The prevention of Cirrhosis can prevent the development of HCC and progression from chronic HCV infection to advanced fibrosis or cirrhosis may be prevented in 40% of patients who are sustained responders to new antiviral strategies, such as pegylated interferon and ribavirin.
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AASLD guidelines for the treatment of hepatocellular carcinoma
Julie K. Heimbach,Laura Kulik,Richard S. Finn,Claude B. Sirlin,Michael Abecassis,Lewis R. Roberts,Andrew X. Zhu,M. Hassan Murad,Jorge A. Marrero +8 more
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, as to provide real-time information about concrete mechanical properties such as E-modulus and compressive strength.
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Chronic hepatitis B: Update 2009
Anna S.F. Lok,Brian J. McMahon +1 more
TL;DR: The 2009 update of the American Association for the Study of Liver Diseases (AASLD) Practice Guidelines for Management of Chronic Hepatitis B is now posted online at www.aasld.org, and the recommendation for first-line oral antiviral medications has been changed to tenofovir or entecavir, and adefovir has been moved to second-line Oral antiviral medication.
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Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
TL;DR: More efficacious treatments, mass immunization programs, and safe injection techniques are essential for eliminating HBV infection and reducing global HBV‐related morbidity and mortality.
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