Use of liposomes as drug delivery vehicles for treatment of melanoma
TLDR
Liposomes delivering chemotherapies, siRNA, asODNs, DNA, and radioactive particles are just some of the promising new nanotechnology based therapies under development for the treatment of melanoma that are discussed in this review.Abstract:
Melanoma is a progressive disease that claims many lives each year due to lack of therapeutics effective for the long-term treatment of patients. Currently, the best treatment option is early detection followed by surgical removal. Better melanoma therapies that are effectively delivered to tumors with minimal toxicity for patients are urgently needed. Nanotechnologies provide one approach to encapsulate therapeutic agents leading to improvements in circulation time, enhanced tumor uptake, avoidance of the reticulo-endothelial system, and minimization of toxicity. Liposomes in particular are a promising nanotechnology that can be used for more effective delivery of therapeutic agents to treat melanoma. Liposomes delivering chemotherapies, siRNA, asODNs, DNA, and radioactive particles are just some of the promising new nanotechnology based therapies under development for the treatment of melanoma that are discussed in this review.read more
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Skin cancer and new treatment perspectives: a review.
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A Review on Composite Liposomal Technologies for Specialized Drug Delivery
Maluta Steven Mufamadi,Viness Pillay,Yahya E. Choonara,Lisa C. du Toit,Girish Modi,Dinesh Naidoo,Valence M. K. Ndesendo +6 more
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Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems
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RNAi-based nanomedicines for targeted personalized therapy.
TL;DR: Progress in designing targeted nano-scaled strategies that are anticipated to overcome the delivery drawbacks and along with the exciting "omics" discipline to personalize RNAi-based therapeutics are introduced.
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