Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos
TLDR
In Drosophila embryos, Cdk1 positive feedback serves primarily to ensure the rapid onset of mitosis, while wave propagation is regulated by S phase events, demonstrating a fundamental distinction between S phase Cdk 1 waves, which propagate as active trigger waves in an excitable medium, and mitotic Cdk2 waves, who propagate as passive phase waves.About:
This article is published in Developmental Cell.The article was published on 2016-08-22 and is currently open access. It has received 118 citations till now. The article focuses on the topics: Wave propagation.read more
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The geometry of biological time , by A. T. Winfree. Pp 544. DM68. Corrected Second Printing 1990. ISBN 3-540-52528-9 (Springer)
TL;DR: In this paper, the authors describe the rules of the ring, the ring population, and the need to get off the ring in order to measure the movement of a cyclic clock.
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Measurement of molecular diffusion in solution by multiphoton fluorescence photobleaching recovery
TL;DR: In this article, the authors proposed a multiphoton fluorescence photobleaching recovery (MP-FPR) technique for measuring the 3D mobility of fluorescent molecules with 3D spatial resolution of a few microns.
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Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis.
Shelby A. Blythe,Eric Wieschaus +1 more
TL;DR: It is found that regions of accessibility are established sequentially, where enhancers are opened in advance of promoters and insulators, and stably maintained in highly condensed mitotic chromatin to ensure faithful inheritance of prior accessibility status across cell divisions.
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Dissipative structures in biological systems: bistability, oscillations, spatial patterns and waves
TL;DR: How relevant is the concept of dissipative structure for understanding the dynamical bases of non-equilibrium self-organization in biological systems, and to see where it has been applied in the five decades since it was initially proposed by Ilya Prigogine?
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Chemical waves in cell and developmental biology
TL;DR: Deneke and Di Talia review how the spatiotemporal coordination of cellular functions across large distances is controlled by chemical waves.
References
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Journal ArticleDOI
The geometry of biological time , by A. T. Winfree. Pp 544. DM68. Corrected Second Printing 1990. ISBN 3-540-52528-9 (Springer)
TL;DR: In this paper, the authors describe the rules of the ring, the ring population, and the need to get off the ring in order to measure the movement of a cyclic clock.
Book
The geometry of biological time
TL;DR: The Varieties of Phaseless Experience: In Which the Geometrical Orderliness of Rhythmic Organization Breaks Down in Diverse Ways is presented.
Journal ArticleDOI
Nonlinear Dynamics and Chaos: With Applications to Physics, Biology, Chemistry and Engineering
TL;DR: This book discusses Chaos, Fractals, and Dynamics, and the Importance of Being Nonlinear in a Dynamical View of the World, which aims to clarify the role of Chaos in the world the authors live in.
Journal ArticleDOI
Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis
V.E. Foe,B.M. Alberts +1 more
TL;DR: Using differential interference contrast optics, combined with cinematography, the morphological changes that the living, syncytial embryo undergoes from stage 10 through 14 of Drosophila embryogenesis, that is just prior to and during formation of the cellular blastoderm are studied.
Journal ArticleDOI
Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis
Olivier Gavet,Jonathon Pines +1 more
TL;DR: It is demonstrated that different levels of CyclinB1-Cdk1 kinase activity trigger different mitotic events, thus revealing how the remarkable reorganization of the cell is coordinated at mitotic entry.
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Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis
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