Audrey Thurm

TL;DR: The largest exome sequencing study of autism spectrum disorder (ASD) to date, using an enhanced analytical framework to integrate de novo and case-control rare variation, identifies 102 risk genes at a false discovery rate of 0.1 or less, consistent with multiple paths to an excitatory-inhibitory imbalance underlying ASD.

TL;DR: A specific model in which negative parenting mediates the relation between economic stressors and psychological symptoms in young people is tested, which generally provides support for the specific model as well as for the broader model.

TL;DR: D diagnostic stability at age 9 years was very high for autism at age 2 years and less strong for pervasive developmental disorder not otherwise specified and Judgment of experienced clinicians, trained on standard instruments, consistently added to information available from parent interview and standardized observation.

TL;DR: Research on the association between stressors and symptoms of psychopathology in children and adolescents with a focus on measurement issues and prospective effects suggests that stressors predict changes in rates of symptoms of psychopathy over time.

TL;DR: There is substantial evidence for the mediating role of family relationship in the relation between stressors and child and adolescent psychological symptoms and future studies should integrate moderator and mediator research by testing for specific mediators in relation to particular moderating contexts, to better understand the complex ways in which stressful life experiences affect the well-being of children and adolescents.