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Marie Bækvad-Hansen

Researcher at Lundbeck

Publications -  49
Citations -  9353

Marie Bækvad-Hansen is an academic researcher from Lundbeck. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 19, co-authored 38 publications receiving 5788 citations. Previous affiliations of Marie Bækvad-Hansen include Trinity College, Dublin & Statens Serum Institut.

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Naomi R. Wray, +262 more
- 26 Apr 2018 - 
TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Ditte Demontis, +126 more
- 01 Jan 2019 - 
TL;DR: A genome-wide association meta-analysis of 20,183 individuals diagnosed with ADHD and 35,191 controls identifies variants surpassing genome- wide significance in 12 independent loci and implicates neurodevelopmental pathways and conserved regions of the genome as being involved in underlying ADHD biology.
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Antonio F. Pardiñas, +90 more
- 26 Feb 2018 - 
TL;DR: A new genome-wide association study of schizophrenia is reported, and through meta-analysis with existing data and integrating genomic fine-mapping with brain expression and chromosome conformation data, 50 novel associated loci and 145 loci are identified.
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Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

F. Kyle Satterstrom, +201 more
- 06 Feb 2020 - 
TL;DR: The largest exome sequencing study of autism spectrum disorder (ASD) to date, using an enhanced analytical framework to integrate de novo and case-control rare variation, identifies 102 risk genes at a false discovery rate of 0.1 or less, consistent with multiple paths to an excitatory-inhibitory imbalance underlying ASD.
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Genome-wide association study identifies 30 loci associated with bipolar disorder

Eli A. Stahl, +342 more
- 01 May 2019 - 
TL;DR: Genome-wide analysis identifies 30 loci associated with bipolar disorder, allowing for comparisons of shared genes and pathways with other psychiatric disorders, including schizophrenia and depression.