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Bruce W. Birren
Researcher at Broad Institute
Publications - 215
Citations - 125222
Bruce W. Birren is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 103, co-authored 205 publications receiving 113491 citations. Previous affiliations of Bruce W. Birren include Massachusetts Institute of Technology & California Institute of Technology.
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Journal ArticleDOI
SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases.
Yuko S. Askew,Stephen C. Pak,Cliff J. Luke,David J. Askew,Sule Cataltepe,David R. Mills,Hiroshi Kato,Jessica A. Lehoczky,Ken Dewar,Bruce W. Birren,Gary A. Silverman +10 more
TL;DR: Data show that SERPINB12 encodes for a new functional member of the human ov-serpin family, which appeared to be an inhibitor of trypsin-like serine proteinases.
Journal ArticleDOI
Corrigendum: Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea (Nature Biotechnology (2017) 35 (725-731) DOI: 10.1038/nbt.3893)
Robert M. Bowers,Nikos C. Kyrpides,Ramunas Stepanauskas,Miranda Harmon-Smith,Devin F. R. Doud,T. B. K. Reddy,Frederik Schulz,Jessica K. Jarett,Adam R. Rivers,Emiley A. Eloe-Fadrosh,Susannah G. Tringe,Natalia Ivanova,Alex Copeland,Alicia Clum,Eric D. Becraft,Rex R. Malmstrom,Bruce W. Birren,Mircea Podar,Peer Bork,George M. Weinstock,George M. Garrity,Jeremy A. Dodsworth,Shibu Yooseph,Granger G. Sutton,Frank Oliver Glöckner,Jack A. Gilbert,William C. Nelson,Steven J. Hallam,Sean P. Jungbluth,Thijs J. G. Ettema,Scott Tighe,Konstantinos T. Konstantinidis,Wen Tso Liu,Brett J. Baker,Thomas Rattei,Jonathan A. Eisen,Brian P. Hedlund,Katherine D. McMahon,Noah Fierer,Rob Knight,Robert D. Finn,Guy Cochrane,Ilene Karsch-Mizrachi,Gene W. Tyson,Christian Rinke,Alla Lapidus,Folker Meyer,Pelin Yilmaz,Donovan H. Parks,A. M. Eren,Lynn M. Schriml,Jillian F. Banfield,Philip Hugenholtz,Tanja Woyke +53 more
TL;DR: In the version of this article initially published, the author A.L. Murat Eren was listed as A.M.
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Ier5, a novel member of the slow-kinetics immediate-early genes.
Max Williams,Myung-Soo Lyu,Yun-Liang Yang,Edward P. Lin,Roland L. Dunbrack,Bruce W. Birren,James M. Cunningham,Kent W. Hunter +7 more
TL;DR: The predicted nuclear localization of Ier5, coupled with the potential for rapid regulation by phosphorylation and/or degradation, suggests that Ier 5 may play an important role in mediating the cellular response to mitogenic signals.
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Whole-Genome Sequencing of Mycobacterium tuberculosis Provides Insight into the Evolution and Genetic Composition of Drug-Resistant Tuberculosis in Belarus.
Kurt Wollenberg,Christopher A. Desjardins,Aksana Zalutskaya,Vervara Slodovnikova,Andrew J. Oler,Mariam Quinones,Thomas Abeel,Sinéad B. Chapman,Michael Tartakovsky,Andrei Gabrielian,Sven Hoffner,Aliaksandr Skrahin,Bruce W. Birren,Alex Rosenthal,Alena Skrahina,Ashlee M. Earl +15 more
TL;DR: It is estimated that the majority of MDR-TB was due to the recent transmission of already-resistant M. tuberculosis strains rather than repeated de novo evolution of resistance within patients, while XDR- TB was acquired through both routes.
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Probing Plasmodium falciparum sexual commitment at the single-cell level
Nicolas M. B. Brancucci,Nicolas M. B. Brancucci,Mariana De Niz,Timothy J. Straub,Timothy J. Straub,Deepali Ravel,Lauriane Sollelis,Bruce W. Birren,Till S. Voss,Till S. Voss,Daniel E. Neafsey,Daniel E. Neafsey,Matthias Marti,Matthias Marti +13 more
TL;DR: This proof-of-concept study provides a template to capture transcriptional diversity in parasite populations containing complex mixtures of different life-cycle stages and developmental programs, with important implications for the understanding of parasite biology and the ongoing malaria elimination campaign.