C
Chantal B.E.M. Reusken
Researcher at Erasmus University Rotterdam
Publications - 52
Citations - 13819
Chantal B.E.M. Reusken is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 22, co-authored 27 publications receiving 10420 citations. Previous affiliations of Chantal B.E.M. Reusken include Erasmus University Medical Center.
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Journal ArticleDOI
Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR.
Victor M. Corman,Olfert Landt,Marco Kaiser,Richard Molenkamp,Adam Meijer,Daniel K.W. Chu,Tobias Bleicker,Sebastian Brünink,Julia Schneider,Marie Luisa Schmidt,Daphne G.J.C. Mulders,Bart L. Haagmans,Bas van der Veer,Sharon van den Brink,Lisa Wijsman,Gabriel Goderski,Jean Louis Romette,Joanna Ellis,Maria Zambon,Malik Peiris,Herman Goossens,Chantal B.E.M. Reusken,Marion Koopmans,Christian Drosten +23 more
TL;DR: A validated diagnostic workflow for 2019-nCoV is presented, its design relying on close genetic relatedness of 2019- nCoV with SARS coronavirus, making use of synthetic nucleic acid technology.
Journal ArticleDOI
Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Patients
Nisreen M.A. Okba,Marcel A. Müller,Wentao Li,Chunyan Wang,Corine H. GeurtsvanKessel,Victor M. Corman,Mart M. Lamers,Reina S. Sikkema,Erwin de Bruin,Felicity D. Chandler,Yazdan Yazdanpanah,Quentin Le Hingrat,Diane Descamps,Nadhira Houhou-Fidouh,Chantal B.E.M. Reusken,Berend Jan Bosch,Christian Drosten,Marion Koopmans,Bart L. Haagmans +18 more
TL;DR: It is demonstrated that most PCR-confirmed SARS-CoV-2–infected persons seroconverted by 2 weeks after disease onset, and validated and tested various antigens in different in-house and commercial ELISAs, finding that commercial S1 IgG or IgA ELISA were of lower specificity, and sensitivity varied between the 2 assays; the IgAELISA showed higher sensitivity.
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BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity
Rob J.W. Arts,Simone J.C.F.M. Moorlag,Boris Novakovic,Yang Li,Shuang-Yin Wang,Marije Oosting,Vinod Kumar,Ramnik J. Xavier,Cisca Wijmenga,Leo A. B. Joosten,Chantal B.E.M. Reusken,Christine Stabell Benn,Christine Stabell Benn,Peter Aaby,Peter Aaby,Marion Koopmans,Hendrik G. Stunnenberg,Reinout van Crevel,Mihai G. Netea,Mihai G. Netea +19 more
TL;DR: BCG vaccination induced genome-wide epigenetic reprograming of monocytes and protected against experimental infection with an attenuated yellow fever virus vaccine strain, with a key role for IL-1β as a mediator of trained immunity responses.
Journal ArticleDOI
Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study
Chantal B.E.M. Reusken,Bart L. Haagmans,Marcel A. Müller,Carlos Gutierrez,Gert Jan Godeke,Benjamin Meyer,Doreen Muth,V. Stalin Raj,Laura Smits De Vries,Victor M. Corman,Jan Felix Drexler,Saskia L. Smits,Yasmin El Tahir,Rita de Sousa,Janko van Beek,Norbert Nowotny,Norbert Nowotny,Kees van Maanen,Ezequiel Hidalgo-Hermoso,Berend Jan Bosch,Peter J. M. Rottier,Albert D. M. E. Osterhaus,Christian Gortázar-Schmidt,Christian Drosten,Marion Koopmans +24 more
TL;DR: Both titres and seroprevalences in sera from different locations in Oman suggest widespread infection of camel populations, and possible animal reservoirs of MERS-CoV are investigated by assessing specific serum antibodies in livestock.
Journal ArticleDOI
Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation
Bart L. Haagmans,Said H.S. Al Dhahiry,Chantal B.E.M. Reusken,V. Stalin Raj,Monica Galiano,Richard M. Myers,Gert Jan Godeke,Marcel Jonges,Elmoubasher Farag,Ayman Diab,Hazem Ghobashy,Farhoud Alhajri,Mohamed H. Al-Thani,Salih A. Al-Marri,Hamad Eid Al Romaihi,Abdullatif Al Khal,Alison Bermingham,Albert D. M. E. Osterhaus,Mohd M. AlHajri,Marion Koopmans +19 more
TL;DR: This study provides virological confirmation of MERS-CoV in camels and suggests a recent outbreak affecting both human beings and camels.