H
Hilary W. Heuer
Researcher at University of California, San Francisco
Publications - 73
Citations - 2889
Hilary W. Heuer is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Frontotemporal dementia. The author has an hindex of 20, co-authored 45 publications receiving 1781 citations. Previous affiliations of Hilary W. Heuer include University of California, Davis.
Papers
More filters
Journal ArticleDOI
Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration.
Elisabeth H. Thijssen,Elisabeth H. Thijssen,Renaud La Joie,Amy Wolf,Amelia Strom,Ping Wang,Leonardo Iaccarino,Viktoriya Bourakova,Yann Cobigo,Hilary W. Heuer,Salvatore Spina,Lawren VandeVrede,Xiyun Chai,Nicholas K. Proctor,David C. Airey,Sergey Shcherbinin,Cynthia Duggan Evans,John R. Sims,Henrik Zetterberg,Kaj Blennow,Kaj Blennow,Anna Karydas,Charlotte E. Teunissen,Joel H. Kramer,Lea T. Grinberg,William W. Seeley,Howie Rosen,Bradley F. Boeve,Bruce L. Miller,Gil D. Rabinovici,Jeffrey L. Dage,Julio C. Rojas,Adam L. Boxer +32 more
TL;DR: Plasma pTau181 concentrations are elevated specifically in patients diagnosed with Alzheimer’s disease compared to those diagnosed with frontotemporal lobar degeneration or elderly controls, supporting its further development as a blood-based biomarker for AD.
Journal ArticleDOI
Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial
Adam L. Boxer,Anthony E. Lang,Murray Grossman,David S. Knopman,Bruce L. Miller,Lon S. Schneider,Rachelle S. Doody,Andrew J. Lees,Lawrence I. Golbe,David R. Williams,Jean-Christophe Corvol,Albert C. Ludolph,David J. Burn,Stefan Lorenzl,Irene Litvan,Erik D. Roberson,Günter U. Höglinger,Mary Koestler,Clifford R. Jack,Viviana M. Van Deerlin,Christopher Randolph,Iryna Lobach,Hilary W. Heuer,Illana Gozes,Lesley Parker,Steve Whitaker,Joe Hirman,Alistair J Stewart,Michael Gold,Bruce H. Morimoto +29 more
TL;DR: Davunetide is not an effective treatment for PSP and clinical trials of disease-modifying treatment are feasible in patients with PSP and should be pursued with other promising tau-directed treatments.
Journal ArticleDOI
Spatial summation in the receptive fields of MT neurons.
TL;DR: The spatial extent over which one stimulus would divide the response to another and found effective normalization from stimuli quite far removed from the RF center is found, which supports models under which normalization occurs both in MT and in earlier stages.
Journal ArticleDOI
Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study.
Elisabeth H. Thijssen,Renaud La Joie,Amelia Strom,Corrina Fonseca,Leonardo Iaccarino,Amy Wolf,Salvatore Spina,Isabel E. Allen,Yann Cobigo,Hilary W. Heuer,Lawren VandeVrede,Nicholas K. Proctor,Argentina Lario Lago,Suzanne L. Baker,Rajeev Sivasankaran,Agnieszka Kieloch,Arvind Kinhikar,Lili Yu,Marie-Anne Valentin,Andreas Jeromin,Henrik Zetterberg,Oskar Hansson,Niklas Mattsson-Carlgren,Danielle Graham,Kaj Blennow,Joel H. Kramer,Lea T. Grinberg,William W. Seeley,Howard J. Rosen,Bradley F. Boeve,Bruce L. Miller,Charlotte E. Teunissen,Gil D. Rabinovici,Julio C. Rojas,Jeffrey L. Dage,Adam L. Boxer,Treatment for Frontotemporal Lobar Degeneration investigators +36 more
TL;DR: In this article, the diagnostic value of both biomarkers in cognitively unimpaired participants and patients with a clinical diagnosis of mild cognitive impairment, Alzheimer's disease syndromes, or frontotemporal lobar degeneration (FTLD) was compared.
Journal ArticleDOI
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.
Katrina M. Moore,Jennifer M. Nicholas,Murray Grossman,Corey T. McMillan,David J. Irwin,Lauren Massimo,Vivianna M. Van Deerlin,Jason D. Warren,Nick C. Fox,Martin N. Rossor,Simon Mead,Martina Bocchetta,Bradley F. Boeve,David S. Knopman,Neill Graff-Radford,Leah K. Forsberg,Rosa Rademakers,Zbigniew K. Wszolek,John C. van Swieten,Lize C. Jiskoot,Lieke H.H. Meeter,Elise G.P. Dopper,Janne M. Papma,Julie S. Snowden,Jennifer A. Saxon,Matthew Jones,Stuart Pickering-Brown,Isabelle Le Ber,Agnès Camuzat,Alexis Brice,Paola Caroppo,Roberta Ghidoni,Michela Pievani,Luisa Benussi,Giuliano Binetti,Bradford C. Dickerson,Diane Lucente,Samantha Krivensky,Caroline Graff,Linn Öijerstedt,Marie Fallström,Håkan Thonberg,Nupur Ghoshal,John C. Morris,Barbara Borroni,Alberto Benussi,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Ian R. Mackenzie,Ging-Yuek Robin Hsiung,Pheth Sengdy,Adam L. Boxer,Howie Rosen,Joanne Taylor,Matthis Synofzik,Matthis Synofzik,Carlo Wilke,Carlo Wilke,Patricia Sulzer,Patricia Sulzer,John R. Hodges,Glenda M. Halliday,John B.J. Kwok,Raquel Sánchez-Valle,Albert Lladó,Sergi Borrego-Écija,Isabel Santana,Maria Rosário Almeida,Miguel Tábuas-Pereira,Fermin Moreno,Myriam Barandiaran,Begoña Indakoetxea,Johannes Levin,Johannes Levin,Adrian Danek,James B. Rowe,Thomas E. Cope,Markus Otto,Sarah Anderl-Straub,Alexandre de Mendonça,Carolina Maruta,Mario Masellis,Sandra E. Black,Philippe Couratier,Géraldine Lautrette,Edward D. Huey,Sandro Sorbi,Benedetta Nacmias,Robert Laforce,Marie Pier L. Tremblay,Rik Vandenberghe,Philip Van Damme,Philip Van Damme,Emily Rogalski,Sandra Weintraub,Alexander Gerhard,Alexander Gerhard,Chiadi U. Onyike,Simon Ducharme,Sokratis G. Papageorgiou,Adeline Su Lyn Ng,Amy Brodtmann,Elizabeth Finger,Rita Guerreiro,Jose Bras,Jonathan D. Rohrer,Carolin Heller,Rhian S Convery,Ione O.C. Woollacott,Rachelle Shafei,Jonathan Graff-Radford,David T.W. Jones,Christina Dheel,Rodolfo Savica,Maria I. Lapid,Matt Baker,Julie A. Fields,Ralitza H. Gavrilova,Kimiko Domoto-Reilly,Jackie M. Poos,Emma L. van der Ende,Jessica L. Panman,Laura Donker Kaat,Harro Seelaar,Anna Richardson,Giovanni B. Frisoni,Anna Mega,Silvia Fostinelli,Huei Hsin Chiang,Antonella Alberici,Andrea Arighi,Chiara Fenoglio,Hilary W. Heuer,Bruce L. Miller,Anna Karydas,Jamie Fong,Maria João Leitão,Beatriz Santiago,Diana Duro,Carlos Ferreira,Alazne Gabilondo,Maria de Arriba,Mikel Tainta,Miren Zulaica,Catarina S. Ferreira,Elisa Semler,Albert C. Ludolph,Bernhard Landwehrmeyer,Alexander E Volk,Gabriel Miltenberger,Ana Verdelho,Sónia Afonso,Maria Carmela Tartaglia,Morris Freedman,Ekaterina Rogaeva,Camilla Ferrari,Irene Piaceri,Valentina Bessi,Gemma Lombardi,Frédéric St-Onge,Marie Claire Doré,Rose Bruffaerts,Mathieu Vandenbulcke,Jan Van den Stock,M.-Marsel Mesulam,Eileen H. Bigio,Christos Koros,John Papatriantafyllou,Christos Kroupis,Leonidas Stefanis,Christien Shoesmith,Erik Robertson,Giovanni Coppola,Eliana Marisa Ramos,Daniel H. Geschwind +177 more
TL;DR: An international study of age at symptom onset, age at death, and disease duration in individuals with mutations in GRN, MAPT, and C9orf72 to investigate the extent to which variability in age at onset and at death could be accounted for by family membership and the specific mutation carried.