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Christa L. Feasley
Researcher at University of Oklahoma Health Sciences Center
Publications - 18
Citations - 642
Christa L. Feasley is an academic researcher from University of Oklahoma Health Sciences Center. The author has contributed to research in topics: Glycan & Glycoprotein. The author has an hindex of 11, co-authored 17 publications receiving 588 citations. Previous affiliations of Christa L. Feasley include Purdue University.
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Journal ArticleDOI
Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
Richard Sucgang,Alan Kuo,Xiangjun Tian,William J Salerno,Anup Parikh,Christa L. Feasley,Eileen Dalin,Hank Tu,Eryong Huang,Kerrie Barry,Erika Lindquist,Harris Shapiro,David G Bruce,Jeremy Schmutz,Asaf Salamov,Petra Fey,Pascale Gaudet,Christophe Anjard,M. Madan Babu,S. Basu,Yulia A. Bushmanova,Hanke van der Wel,Mariko Katoh-Kurasawa,Christopher Dinh,Pedro M. Coutinho,Tamao Saito,Marek Eliáš,Pauline Schaap,Robert R. Kay,Bernard Henrissat,Ludwig Eichinger,Francisco Rivero,Nicholas H. Putnam,Christopher M. West,William F. Loomis,Rex L. Chisholm,Gad Shaulsky,Gad Shaulsky,Joan E. Strassmann,David C. Queller,Adam Kuspa,Adam Kuspa,Igor V. Grigoriev +42 more
TL;DR: Genes involved in the social stage evolved more rapidly than others, consistent with either relaxed selection or accelerated evolution due to social conflict, and shed light on the biology and evolution of the Dictyostelia.
Journal ArticleDOI
Glycan reductive isotope labeling for quantitative glycomics
TL;DR: This technique allows linear relative quantitation of glycans over a 10-fold concentration range and can accurately quantify sub-picomole levels of released glycans, providing a needed advancement in the field of glycomics.
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Ligand reduces galectin-1 sensitivity to oxidative inactivation by enhancing dimer formation.
Sean R. Stowell,Moonjae Cho,Christa L. Feasley,Connie M. Arthur,Xuezheng Song,Jennifer K. Colucci,Sougata Karmakar,Padmaja Mehta,Marcelo Dias-Baruffi,Rodger P. McEver,Rodger P. McEver,Richard D. Cummings +11 more
TL;DR: Results demonstrate that monomer-dimer equilibrium regulatesGal-1 sensitivity to oxidative inactivation and provides a mechanism whereby ligand partially protects Gal-1 from oxidation.
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The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles
Albert Nguyen,Christa L. Feasley,Kenneth W. Jackson,Theodore J. Nitz,Karl Salzwedel,Gillian M. Air,Michael Sakalian +6 more
TL;DR: This is the first demonstration of a direct interaction between the maturation inhibitor, bevirimat, and its target, Gag and extensive prior genetic evidence suggests that the MHR is critical for virus assembly.
Journal ArticleDOI
Bacillus anthracis Peptidoglycan Stimulates an Inflammatory Response in Monocytes through the p38 Mitogen-Activated Protein Kinase Pathway
Marybeth Langer,Alexander Malykhin,Kenichiro Maeda,Kaushik Chakrabarty,Kelly S. Williamson,Christa L. Feasley,Christopher M. West,Jordan P. Metcalf,K. Mark Coggeshall +8 more
TL;DR: Peptidoglycan in B. anthracis is biologically active, that it stimulates a proinflammatory response in monocytes, and uses the p38 kinase signal transduction pathway to do so, suggesting that the inflammatory events associated with peptidogly can may play an important role in anthrax pathogenesis.