Mariko Katoh-Kurasawa

TL;DR: These findings suggest that developmental programs are remarkably conserved at the transcriptome level, considering the great evolutionary distance between the genomes.

TL;DR: Genes involved in the social stage evolved more rapidly than others, consistent with either relaxed selection or accelerated evolution due to social conflict, and shed light on the biology and evolution of the Dictyostelia.

TL;DR: This work reveals a decoding mechanism by which oscillatory signals are used to guide gene expression and promote timely development and demonstrates that this regulatory mechanism enables cells to modulate gene expression by counting low-frequency stimulations but filtering out high-frequency signals.

TL;DR: This work found that the developmental transcriptome exhibits mostly gradual changes interspersed by a few instances of large shifts, and described D. discoideum development as a series of coordinated cellular and multicellular activities.

TL;DR: The results reveal the evolutionary dynamics of cooperation and cheating and underscore how sequence-based approaches can be used to elucidate the history of conflicts that are difficult to observe directly.