Ivan Balascak

TL;DR: This analysis revealed that the genetic structure of the European population correlates closely with geography, and allows the creation of a comprehensive European genetic map that will greatly facilitate inter-population genetic studies including genome wide association studies (GWAS).

TL;DR: The mechanism by which CPA1 variants confer increased pancreatitis risk may involve misfolding-induced endoplasmic reticulum stress rather than elevated trypsin activity, as is seen with other genetic risk factors for this disease.

TL;DR: A protective effect of the placental barrier against the genotoxic effect of some tobacco smoke components between the circulation of mother and child is suggested.

TL;DR: Functional annotation analysis suggested processes and pathways affected by tobacco smoke exposure that may represent molecular mechanisms of smoke-induced placental abnormalities.

TL;DR: Higher lipid peroxidation in newborns than in mothers, close correlation of analyzed oxidative stress markers between newborns and mothers, and a relationship between oxidative stress and induction of DNA adducts are shown.