Christian V. Stevens

TL;DR: The structural diversity of these pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones resulted in significant variation in the biopharmaceutical properties, reflected by the broad range in fasted state simulated intestinal fluid solubility values, Caco-2 permeability coefficients and in vitro-predicted human in vivo intrinsic clearance values.

TL;DR: In this article, the authors provide an overview of the nitrogen-rich antennae in lanthanide-based temperature sensors, emitting in the visible light spectrum, and discuss their temperature sensor ability.

TL;DR: In this article, a new class of lipid lamellar hydrogels composed of one single bolaform glycosylated lipid obtained by fermentation is reported. And the authors show that ionic strength is not only necessary, as one could expect, to control the interactions in the laminar phase but, most importantly, it directly controls the elastic properties of the gels.

TL;DR: The synthesis and pharmaceutical properties of pyrrolopyrimidines have been summarized in this paper, where the authors present a review of recent literature on pyrrole-based scaffolds.

TL;DR: A short and elegant synthetic pathway was developed for the synthesis of 1,3-dioxo-hexahydropyrido[1,2-c][1,3]diazepine carboxylates, a new 1, 3-diazepan-2,4-dione containing bicyclic moiety, starting from pyroglutamate esters.