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Christopher H. Calvey
Researcher at Great Lakes Bioenergy Research Center
Publications - 6
Citations - 2710
Christopher H. Calvey is an academic researcher from Great Lakes Bioenergy Research Center. The author has contributed to research in topics: Genomics & Fermentation. The author has an hindex of 5, co-authored 5 publications receiving 2403 citations. Previous affiliations of Christopher H. Calvey include University of Wisconsin-Madison & J. Craig Venter Institute.
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Journal ArticleDOI
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
Daniel G. Gibson,John I. Glass,Carole Lartigue,Vladimir N. Noskov,Ray-Yuan Chuang,Mikkel A. Algire,Gwynedd A. Benders,Michael G. Montague,Li Ma,Monzia Moodie,Chuck Merryman,Sanjay Vashee,Radha Krishnakumar,Nacyra Assad-Garcia,Cynthia Andrews-Pfannkoch,Evgeniya A. Denisova,Lei Young,Zhi-Qing Qi,Thomas H. Segall-Shapiro,Christopher H. Calvey,Prashanth P. Parmar,Clyde A. Hutchison,Hamilton O. Smith,J. Craig Venter +23 more
TL;DR: The design, synthesis, and assembly of the 1.08–mega–base pair Mycoplasma mycoides JCVI-syn1.0 genome starting from digitized genome sequence information and its transplantation into a M. capricolum recipient cell to create new cells that are controlled only by the synthetic chromosome are reported.
Journal ArticleDOI
Comparative genomics of biotechnologically important yeasts
Robert Riley,Sajeet Haridas,Kenneth H. Wolfe,Mariana R. Lopes,Chris Todd Hittinger,Markus Göker,Asaf Salamov,Jennifer H. Wisecaver,Tanya M Long,Christopher H. Calvey,Andrea Aerts,Kerrie Barry,Cindy Choi,Alicia Clum,Aisling Y. Coughlan,Shweta Deshpande,Alexander P Douglass,Sara J Hanson,Hans-Peter Klenk,Kurt LaButti,Alla Lapidus,Erika Lindquist,Anna Lipzen,Jan P. Meier-Kolthoff,Robin A. Ohm,Robert Otillar,Jasmyn Pangilinan,Yi Peng,Antonis Rokas,Carlos A. Rosa,Carmen Scheuner,Andriy A. Sibirny,Jason C. Slot,J. Benjamin Stielow,Hui Sun,Cletus P. Kurtzman,Meredith Blackwell,Igor V. Grigoriev,Thomas W. Jeffries +38 more
TL;DR: The comparative genome analysis of 29 taxonomically and biotechnologically important yeasts, including 16 newly sequenced, enables correlation of genes to useful metabolic properties and showed the synteny of the mating-type locus to be conserved over a billion years of evolution.
Journal ArticleDOI
Nitrogen limitation, oxygen limitation, and lipid accumulation in Lipomyces starkeyi.
Christopher H. Calvey,Yi-Kai Su,Yi-Kai Su,Laura B. Willis,Mcsean A. Mcgee,Thomas W. Jeffries,Thomas W. Jeffries,Thomas W. Jeffries +7 more
TL;DR: Under all conditions, L. starkeyi cultures tolerated acidified media, produced considerable amounts of alcohols; including ethanol, mannitol, arabitol, and 2,3-butanediol, showing its potential to produce biofuels from renewable agricultural feedstocks.
Journal ArticleDOI
An optimized transformation protocol for Lipomyces starkeyi
TL;DR: An efficient genetic transformation system for Lipomyces starkeyi based on a modified lithium acetate transformation protocol is reported, achieving efficiencies in excess of 8,000 transformants/µg DNA, which now make it possible to screen libraries in the metabolic engineering of this yeast.
Journal ArticleDOI
Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering
Chen Ling,George L Peabody,Davinia Salvachúa,Young-Mo Kim,Colin M Kneucker,Christopher H. Calvey,Michela A Monninger,Nathalie Muñoz,Brenton C. Poirier,Kelsey J. Ramirez,Peter C. St. John,Sean P. Woodworth,Jon K. Magnuson,Kristin E. Burnum-Johnson,Adam M. Guss,Christopher W. Johnson,Gregg T. Beckham +16 more
TL;DR: In this paper , Pseudomonas putida KT2440 is engineered to convert glucose and xylose, the primary carbohydrates in lignocellulosic hydrolysates, to muconic acid using a model-guided strategy to maximize the theoretical yield.