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Weiming He
Researcher at Beijing Genomics Institute
Publications - 44
Citations - 8500
Weiming He is an academic researcher from Beijing Genomics Institute. The author has contributed to research in topics: Population & Genome. The author has an hindex of 23, co-authored 37 publications receiving 6936 citations. Previous affiliations of Weiming He include Beijing Institute of Genomics & South China University of Technology.
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Journal ArticleDOI
Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
Xin Yi,Yu Liang,Emilia Huerta-Sanchez,Xin Jin,Zha Xi Ping Cuo,John E. Pool,John E. Pool,Xun Xu,Hui Jiang,Nicolas Vinckenbosch,Thorfinn Sand Korneliussen,Hancheng Zheng,Tao Liu,Weiming He,Kui Li,Ruibang Luo,Xifang Nie,Honglong Wu,Meiru Zhao,Hongzhi Cao,Jing Zou,Ying Shan,Shuzheng Li,Qi Yang,Asan,Peixiang Ni,Geng Tian,Junming Xu,Xiao Liu,Tao Jiang,Renhua Wu,Guangyu Zhou,Meifang Tang,Junjie Qin,Tong Wang,Shuijian Feng,Guohong Li,Huasang,Jiangbai Luosang,Wei Wang,Fang Chen,Yading Wang,Xiaoguang Zheng,Zhuo Li,Zhuoma Bianba,Ge Yang,Xiznping Wang,Shuhui Tang,Guoyi Gao,Yong Chen,Zhen Luo,Lamu Gusang,Zheng Cao,Qinghui Zhang,Wei-Han OuYang,Xiaoli Ren,Huiqing Liang,Huisong Zheng,Yebo Huang,Jingxiang Li,Lars Bolund,Karsten Kristiansen,Yingrui Li,Yong Zhang,Xiuqing Zhang,Ruiqiang Li,Songgang Li,Huanming Yang,Rasmus Nielsen,Rasmus Nielsen,Jun Wang,Jing Wang +71 more
TL;DR: A population genomic survey has revealed a functionally important locus in genetic adaptation to high altitude, and the strongest signal of natural selection came from endothelial Per-Arnt-Sim domain protein 1 (EPAS1), a transcription factor involved in response to hypoxia.
Journal ArticleDOI
Draft genome sequence of chickpea ( Cicer arietinum ) provides a resource for trait improvement
Rajeev K. Varshney,Rajeev K. Varshney,Chi Song,Rachit K. Saxena,Sarwar Azam,Sheng Yu,Andrew G. Sharpe,Steven B. Cannon,Jong-Min Baek,Benjamin D. Rosen,Bunyamin Tar’an,Teresa Millán,Xudong Zhang,Larissa Ramsay,Aiko Iwata,Ying Wang,William Nelson,Andrew Farmer,Pooran M. Gaur,Carol Soderlund,R. Varma Penmetsa,Chunyan Xu,Arvind K. Bharti,Weiming He,Peter Winter,Shancen Zhao,James K. Hane,Noelia Carrasquilla-Garcia,Janet A. Condie,Hari D. Upadhyaya,Ming-Cheng Luo,Mahendar Thudi,C. L. L. Gowda,Narendra Singh,Judith Lichtenzveig,Krishna K. Gali,Josefa Rubio,N. Nadarajan,Jaroslav Dolezel,Kailash C. Bansal,Xun Xu,David Edwards,Gengyun Zhang,Guenter Kahl,Juan Gil,Karam B. Singh,Karam B. Singh,Swapan K. Datta,Scott A. Jackson,Jun Wang,Jun Wang,Douglas R. Cook +51 more
TL;DR: This work reports the ∼738-Mb draft whole genome shotgun sequence of CDC Frontier, a kabuli chickpea variety, which contains an estimated 28,269 genes, and identifies targets of both breeding-associated genetic sweeps and breeding- associated balancing selection.
Journal ArticleDOI
Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection
Hon-Ming Lam,Xun Xu,Xin Liu,Wenbin Chen,Guohua Yang,Fuk-Ling Wong,Man-Wah Li,Weiming He,Nan Qin,Bo Wang,Jun Li,Min Jian,Jing Wang,Guihua Shao,Jun Wang,Samuel S. M. Sun,Gengyun Zhang +16 more
TL;DR: A high level of linkage disequilibrium in the soybean genome is identified, suggesting that marker-assisted breeding of soybean will be less challenging than map-based cloning and to facilitate future breeding and quantitative trait analysis.
Journal ArticleDOI
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes
Xun Xu,Xin Liu,Song Ge,Jeffrey D. Jensen,Fengyi Hu,Xin Li,Yang Dong,Ryan N. Gutenkunst,Lin Fang,Lei Huang,Jingxiang Li,Weiming He,Weiming He,Guojie Zhang,Guojie Zhang,Guojie Zhang,Xiaoming Zheng,Fu-Min Zhang,Yingrui Li,Chang Yu,Karsten Kristiansen,Karsten Kristiansen,Xiuqing Zhang,Jian Wang,Mark G. Wright,Susan R. McCouch,Rasmus Nielsen,Rasmus Nielsen,Rasmus Nielsen,Jun Wang,Jun Wang,Wen Wang +31 more
TL;DR: Thousands of genes with significantly lower diversity in cultivated but not wild rice are identified, which represent candidate regions selected during domestication and should be valuable for breeding and for identifying agronomically important genes in rice.
Journal ArticleDOI
Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation
Jizeng Jia,Shancen Zhao,Xiuying Kong,Yingrui Li,Guangyao Zhao,Weiming He,Rudi Appels,Matthias Pfeifer,Yong Tao,Xueyong Zhang,Ruilian Jing,Chi Zhang,Youzhi Ma,Lifeng Gao,Chuan Gao,Manuel Spannagl,Klaus F. X. Mayer,Dong Li,Shengkai Pan,Fengya Zheng,Qun Hu,Xianchun Xia,Jianwen Li,Qinsi Liang,Jie Chen,Thomas Wicker,Caiyun Gou,Hanhui Kuang,Genyun He,Yadan Luo,Beat Keller,Qiuju Xia,Peng Lu,Junyi Wang,Hongfeng Zou,Rongzhi Zhang,Jun-Yang Xu,Jinlong Gao,Christopher P. Middleton,Zhiwu Quan,Guangming Liu,Jian Wang,Huanming Yang,Xu Liu,Zhonghu He,Long Mao,Jun Wang,Jun Wang +47 more
TL;DR: This draft genome sequence provides insight into the environmental adaptation of bread wheat and can aid in defining the large and complicated genomes of wheat species.