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David A. Pearce

Researcher at Northumbria University

Publications -  405
Citations -  20297

David A. Pearce is an academic researcher from Northumbria University. The author has contributed to research in topics: Batten disease & CLN3. The author has an hindex of 72, co-authored 396 publications receiving 18416 citations. Previous affiliations of David A. Pearce include University of Zurich & University of York.

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Spatial pattern in Antarctica: what can we learn from Antarctic bacterial isolates?

TL;DR: This study collated Antarctic bacterial culture identities based on the 16S rRNA gene information available in the literature and the GenBank database, showing that a majority of Antarctic bacterial isolates were highly similar to those retrieved from tropical and temperate regions.
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Microbial metabolism directly affects trace gases in (sub) polar snowpacks

TL;DR: The results suggest that this long-neglected microbial activity could constitute a potential source of error in climate history interpretations, by introducing a so far unappreciated source of bias in the quantification of atmospheric-derived trace gases trapped within the polar ice caps.
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Composition and Interactions among Bacterial, Microeukaryotic, and T4-like Viral Assemblages in Lakes from Both Polar Zones.

TL;DR: The authors' analyses show significant global correlations between bacterial and microeukaryotic community structures, and between the phylogenetic compositions of bacterial and T4-like virus assemblages.
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Cyc2p is required for maintaining ionic stability and efficient cytochrome c import and mitochondrial function in Saccharomyces cerevisiae

TL;DR: It is suggested that Cyc2p serves to maintain the osmotic stability of mitochondria, and its defect is exacerbated by KCl, but is suppressed on media containing sorbitol, a non‐ionic compound.
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Regulation of gastric acid secretion by PKB/Akt2.

TL;DR: Akt2 suppresses gastric acid secretion and contributes to or even accounts for the inhibition of gastric acids secretion by PI3K.