David A. Pearce

TL;DR: The study uncovers some viral lineages with a bipolar distribution, suggesting a global dispersal capacity for viruses, and seemingly indicates that viruses do not follow the latitudinal diversity gradient known for macroorganisms.

TL;DR: This paper evaluates recent progress in Southern Ocean benthic research and identifies priorities for future research, including timely and accurate species identifications, application of standardized sampling and reporting procedures, as well as cooperation between disciplines and nations.

TL;DR: It is reported that lysosomes isolated from juvenile Batten disease lymphoblasts are only defective for arginine transport, suggesting that the CLN3 defect in juvenile batten disease may affect how intracellular levels ofArginine are regulated or distributed throughout the cell.

TL;DR: The Unified Batten Disease Rating Scale (UBDRS) is a reliable instrument that effectively tests for neurologic function in blind and demented patients and is useful for monitoring the diverse clinical findings seen in Batten disease.

TL;DR: The aldosterone-induced increase in sodium reabsorption across tight epithelia can be divided schematically into two functional phases: an early regulatory phase starting after a lag period of 20 to 60 minutes, during which the pre-existing transport machinery is activated, and a late phase which can be viewed as an anabolic action leading to a further amplification/differentiation of the Na+ transport machinery.