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David A. Pearce
Researcher at Northumbria University
Publications - 405
Citations - 20297
David A. Pearce is an academic researcher from Northumbria University. The author has contributed to research in topics: Batten disease & CLN3. The author has an hindex of 72, co-authored 396 publications receiving 18416 citations. Previous affiliations of David A. Pearce include University of Zurich & University of York.
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Journal ArticleDOI
Neuropsychological symptoms of juvenile-onset batten disease: experiences from 2 studies.
Heather R. Adams,Jennifer M. Kwon,Frederick J. Marshall,Elisabeth A. de Blieck,David A. Pearce,Jonathan W. Mink +5 more
TL;DR: Children with genetic or clinicopathologic confirmation of juvenile neuronal ceroid lipofuscinosis exhibited significant and pervasive impairments on tests of auditory attention, verbal memory and repetition, verbal fluency, and an estimate of verbal intellectual ability.
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Linking regional variation of epibiotic bacterial diversity and trophic ecology in a new species of Kiwaidae (Decapoda, Anomura) from East Scotia Ridge (Antarctica) hydrothermal vents
Katrin Zwirglmaier,William D. K. Reid,Jane L. Heywood,C. J. Sweeting,Benjamin D. Wigham,Nicholas Polunin,Jeff A. Hawkes,Douglas P. Connelly,David A. Pearce,David A. Pearce,David A. Pearce,Katrin Linse +11 more
TL;DR: Both stable isotope and sequence data suggest a dominance of different carbon fixation pathways of the epibiont communities at the two vent fields, and co‐varying epibions diversity and isotope values at E2 and E9 present further support for the hypothesis thatEpibionts serve as a food source for Kiwa.
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Location- and sex-specific differences in weight and motor coordination in two commonly used mouse strains
Attila D. Kovács,David A. Pearce +1 more
TL;DR: The results show that environmental factors specific to a geographical location can change the body weight, motor coordination and motor learning capability of wild type mice commonly used as controls in transgenic studies.
Maternal infection leads to abnormal gene regulation and brain atrophy in mouse offspring
S. Hossein Fatemi,Teri J. Reutiman,Timothy D. Folsom,Hao Huang,Kenichi Oishi,Susumu Mori,Donald F. Smee,David A. Pearce,Christine Winter,Reinhard Sohr,Georg Juckel +10 more
TL;DR: It is proposed that maternal infection in mouse provides an heuristic animal model for studying the environmental contributions to genesis of schizophrenia and autism, two important examples of neurodevelopmental disorders.
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Toxic Cyanobacteria in Svalbard: Chemical Diversity of Microcystins Detected Using a Liquid Chromatography Mass Spectrometry Precursor Ion Screening Method.
Julia Kleinteich,Julia Kleinteich,Jonathan Puddick,Susanna A. Wood,Falk Hildebrand,H. Dail Laughinghouse,David A. Pearce,David A. Pearce,Daniel R. Dietrich,Annick Wilmotte +9 more
TL;DR: The LC-MS precursor ion screening method could be useful for microcystin detection in unusual matrices such as benthic biofilms or lichen, and the mcy genes detected showed highest similarities to other Arctic or Antarctic sequences.