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David A. Pearce
Researcher at Northumbria University
Publications - 405
Citations - 20297
David A. Pearce is an academic researcher from Northumbria University. The author has contributed to research in topics: Batten disease & CLN3. The author has an hindex of 72, co-authored 396 publications receiving 18416 citations. Previous affiliations of David A. Pearce include University of Zurich & University of York.
Papers
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Journal ArticleDOI
The identification of environmental parameters which could influence soil bacterial community composition on the Antarctic Peninsula - A statistical approach
TL;DR: Differences in location and soil pH are identified as the environmental variables that could most probably explain the soil bacterial community patterns.
Journal ArticleDOI
Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease
Denia Ramirez-Montealegre,Subrata Chattopadhyay,Timothy M. Curran,Clive Wasserfall,L. Pritchard,Desmond A. Schatz,John M. Petitto,Diane Hopkins,J. X. She,Paul G. Rothberg,Mark A. Atkinson,David A. Pearce +11 more
TL;DR: Batten patients did not possess autoantibodies against other type 1 diabetes-associated autoantigens and human leukocyte antigen genotypes revealed no specific associations with this disease.
Journal ArticleDOI
Transmission electron microscope analysis of virus-like particles in the freshwater lakes of Signy Island, Antarctica
TL;DR: Water samples from a range of fresh-water Antarctic lakes on Signy Island were examined for the presence of virus-like particles (VLPs) during the 1998/1999 field season and it was discovered that VLPs were ubiquitous, morphologically diverse and abundant.
Book ChapterDOI
Probe Technology for the Direct Measurement and Sampling of Ellsworth Subglacial Lake
Matthew C. Mowlem,Maria-Nefeli Tsaloglou,Edward M. Waugh,Cedric F.A. Floquet,Kevin Saw,Lee Fowler,Robin Brown,David A. Pearce,James Wyatt,Alexander Beaton,Mario Brito,Dominic A. Hodgson,Gwyn Griffiths,Michael J. Bentley,David Blake,Linda Capper,Rachel J. Clarke,Charles S. Cockell,Hugh F. J. Corr,William Henry Harris,Christopher S. Hill,Richard C. A. Hindmarsh,Edward C. King,Henry F. Lamb,Barbara A. Maher,Keith Makinson,John Parnell,John C. Priscu,Andrés Rivera,Neil Ross,Martin J. Siegert,Andrew Smith,Andrew Tait,Martyn Tranter,Jemma L. Wadham,Brian Whalley,John Woodward +36 more
TL;DR: A U.K. consortium has planned an extensive logistics and equipment development program that will deliver the necessary resources for direct measurement and sampling of Ellsworth Subglacial Lake and reveal the post-Pliocene history of the West Antarctic Ice Sheet as discussed by the authors.
Journal ArticleDOI
First evidence for a bipolar distribution of dominant freshwater lake bacterioplankton
TL;DR: Arctic freshwater lakes appeared to be dominated by some of the same groups of bacterioplankton thought to be dominant in Antarctic lakes, the vast majority of which represented uncultivated groups.