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Deborah J. Cook

Researcher at McMaster University

Publications -  942
Citations -  165225

Deborah J. Cook is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care & Randomized controlled trial. The author has an hindex of 173, co-authored 907 publications receiving 148928 citations. Previous affiliations of Deborah J. Cook include McMaster University Medical Centre & Queen's University.

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Journal Article

Endoscopic Ligation Compared with Sclerotherapy for Treatment of Esophageal Variceal Bleeding

TL;DR: To critically appraise and synthesize the current evidence on endoscopic ligation for esophageal variceal bleeding, a meta-analysis of the results of randomized clinical trials that compared endoscope ligation with sclerotherapy is done.
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Endoscopic Ligation Compared with Sclerotherapy for Treatment of Esophageal Variceal Bleeding: A Meta-Analysis

TL;DR: In this paper, the effect of endoscopic ligation compared with sclerotherapy in the treatment of patients with bleeding esophageal varices was compared in seven randomized trials.
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Crystalloids vs. colloids in fluid resuscitation: a systematic review.

TL;DR: Overall, there is no apparent difference in pulmonary edema, mortality, or length of stay between isotonic crystalloid and colloid resuscitation between randomized clinical trials of adult patients requiring fluid resuscitation vs. colloids.
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Stress ulcer prophylaxis in critically ill patients. Resolving discordant meta-analyses.

TL;DR: There is strong evidence of reduced clinically important gastrointestinal bleeding with histamine2-receptor antagonists and sucralfate may be as effective in reducing bleeding as gastric pH—altering drugs and is associated with lower rates of pneumonia and mortality.