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Deborah J. Cook
Researcher at McMaster University
Publications - 942
Citations - 165225
Deborah J. Cook is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care & Randomized controlled trial. The author has an hindex of 173, co-authored 907 publications receiving 148928 citations. Previous affiliations of Deborah J. Cook include McMaster University Medical Centre & Queen's University.
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Journal ArticleDOI
Evidence based medicine has come a long way
TL;DR: Important developments in evidence based medicine over the subsequent decade included the increasing popularity of structured abstracts and secondary journals summarising evidence from clinical research and the application of formal rules of evidence in evaluating the clinical literature.
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The RECOVER Program: Disability Risk Groups and 1-Year Outcome after 7 or More Days of Mechanical Ventilation.
Margaret S. Herridge,Leslie M. Chu,Andrea Matte,George Tomlinson,Linda Chan,Claire Thomas,Jan O. Friedrich,Sangeeta Mehta,Francois Lamontagne,Mélanie Levasseur,Niall D. Ferguson,Neill K. J. Adhikari,Jill C. Rudkowski,Hilary Meggison,Yoanna Skrobik,John G. Flannery,Mark Bayley,Jane Batt,Claudia C. dos Santos,Susan E. Abbey,Adrienne Tan,Vincent Lo,Sunita Mathur,Matteo Parotto,Denise Morris,Linda Flockhart,Eddy Fan,Christie M. Lee,M. Elizabeth Wilcox,Najib T. Ayas,Karen Choong,Robert A. Fowler,Damon C. Scales,Tasnim Sinuff,Brian H Cuthbertson,Louise Rose,Priscila Robles,Stacey Burns,Marcelo Cypel,Lianne G. Singer,C. Chaparro,Chung-Wai Chow,Shaf Keshavjee,Laurent Brochard,Paul C. Hébert,Arthur S. Slutsky,John C. Marshall,Deborah J. Cook,Jill I. Cameron,Recover Program Investigators +49 more
TL;DR: ICU survivors of greater than or equal to 1 week of MV may be stratified into four disability groups based on age and ICU length of stay to stratify patients for post-ICU disability and recovery to 1 year after critical illness.
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Does this adult patient have acute meningitis
TL;DR: Among adults with a clinical presentation that is low risk for meningitis, the clinical examination aids in excluding the diagnosis, and clinicians frequently need to proceed directly to lumbar puncture in high-risk patients.
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Withdrawing and withholding life support in the intensive care unit: a Spanish prospective multi-centre observational study
Andrés Esteban,Federico Gordo,J F Solsona,Inmaculada Alía,Julio Caballero,C Bouza,Juan Alcalá-Zamora,Deborah J. Cook,J.M. Sánchez,R. Abizanda,G Miró,M J Fernández Del Cabo,E. de Miguel,J A Santos,Begoña Balerdi +14 more
TL;DR: Age, SAPS II and length of ICU stay were significantly higher in patients Dying patients who had therapy withheld or withdrawn than in patients dying despite active treatment.
Journal ArticleDOI
Stress Ulcer Prophylaxis in Critically Ill Patients Resolving Discordant Meta-Analyses
Deborah J. Cook,Brenda Reeve,Gordon H. Guyatt,Daren K. Heyland,Lauren Griffith,Lisa Buckingham,Michael Tryba +6 more
TL;DR: There is strong evidence of reduced clinically important gastrointestinal bleeding with histamine2-receptor antagonists and sucralfate is as effective in reducing bleeding as gastric pH-altering drugs and is associated with lower rates of pneumonia and mortality.