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Deborah J. Cook
Researcher at McMaster University
Publications - 942
Citations - 165225
Deborah J. Cook is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care & Randomized controlled trial. The author has an hindex of 173, co-authored 907 publications receiving 148928 citations. Previous affiliations of Deborah J. Cook include McMaster University Medical Centre & Queen's University.
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Special Article Toronto critical care medicine symposium report
TL;DR: The Critical Care Symposium as mentioned in this paper reviewed clinical trials with potential practical impact on day-to-day practice and revisited older scientific questions (such as steroids in sepsis) which are now being re-evaluated in a new light.
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Bishomotropyliumionen unter bedingungen fuer lange und kurze lebensdauer
Per Ahlberg,David L. Harris,Mark E. Roberts,P. Warner,P. Seidl,M. Sakai,Deborah J. Cook,A. Diaz,J. P. Dirlam,Helmut Hamberger,Saul Winstein +10 more
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The PROTROPIC feasibility study: prognostic value of elevated troponins in critical illness
Emilie P. Belley-Côté,Richard P. Whitlock,Richard P. Whitlock,Diana V Ulic,Kimia Honarmand,Abubaker Khalifa,Graham R. McClure,Andrew Gibson,Fayez Alshamsi,Frédérick D’Aragon,Bram Rochwerg,Erick Duan,Nevena Savija,Nevena Savija,Tim Karachi,Francois Lamontagne,Peter A. Kavsak,Deborah J. Cook,Deborah J. Cook +18 more
TL;DR: This pilot study has established the feasibility of conducting a large-scale investigation addressing this issue and measured recruitment rate, the proportion of patients who consented under a deferred consent model, and time required for data collection and study procedures.
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FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer’s lactate
Lauralyn McIntyre,Dean Fergusson,Tracy McArdle,Alison Fox-Robichaud,Shane W. English,Claudio Martin,John C. Marshall,Deborah J. Cook,Ian D. Graham,Steven Hawken,Colin J. L. McCartney,Kusum Menon,Raphael Saginur,Andrew J.E. Seely,Ian G. Stiell,Kednapa Thavorn,Charles Weijer,Akshai Iyengar,John Muscedere,Alan J. Forster,Monica Taljaard +20 more
TL;DR: The FLUID trial as discussed by the authors was a pilot trial to explore the feasibility of a large trial powered for clinically important outcomes, and the primary feasibility outcome was study fluid protocol adherence, secondary feasibility outcomes included time to Research Ethics Board (REB) approval and trial initiation.
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A randomized trial of combination therapy versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia
TL;DR: The purpose of this study was to determine optimal empiric treatment of VAP by comparing a strategy of combination therapy to monotherapy with broad-spectrum antibiotics.