D
Dita Maixnerova
Researcher at Charles University in Prague
Publications - 37
Citations - 1592
Dita Maixnerova is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Nephropathy & Renal function. The author has an hindex of 15, co-authored 32 publications receiving 1293 citations.
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Journal ArticleDOI
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
Krzysztof Kiryluk,Yifu Li,Francesco Scolari,Simone Sanna-Cherchi,Murim Choi,Miguel Verbitsky,David Fasel,Sneh Lata,Sindhuri Prakash,Samantha Shapiro,Clara Fischman,Holly J. Snyder,Gerald B. Appel,Claudia Izzi,Battista Fabio Viola,Nadia Dallera,Lucia Del Vecchio,Cristina Barlassina,Erika Salvi,Francesca Bertinetto,Antonio Amoroso,Silvana Savoldi,Marcella Rocchietti,Alessandro Amore,Licia Peruzzi,Rosanna Coppo,Maurizio Salvadori,Pietro Ravani,Riccardo Magistroni,Gian Marco Ghiggeri,Gianluca Caridi,Monica Bodria,Francesca Lugani,Landino Allegri,Marco Delsante,Mariarosa Maiorana,Andrea Magnano,Giovanni M. Frascà,Emanuela Boer,Giuliano Boscutti,Claudio Ponticelli,Renzo Mignani,Carmelita Marcantoni,Domenico Di Landro,Domenico Santoro,Antonello Pani,Rosaria Polci,Sandro Feriozzi,Silvana Chicca,Marco Galliani,Maddalena Gigante,Loreto Gesualdo,Pasquale Zamboli,Giovanni Giorgio Battaglia,Maurizio Garozzo,Dita Maixnerova,Vladimir Tesar,Frank Eitner,Thomas Rauen,Jürgen Floege,Tibor Kovács,Judit Nagy,Krzysztof Mucha,Leszek Pączek,Marcin Zaniew,Małgorzata Mizerska-Wasiak,Maria Roszkowska-Blaim,Krzysztof Pawlaczyk,Daniel P. Gale,Jonathan Barratt,Lise Thibaudin,François Berthoux,Guillaume Canaud,Anne Boland,Marie Metzger,Ulf Panzer,Hitoshi Suzuki,Shin Goto,Ichiei Narita,Yasar Caliskan,Jingyuan Xie,Ping Hou,Nan Chen,Hong Zhang,Robert J. Wyatt,Jan Novak,Bruce A. Julian,John Feehally,Bénédicte Stengel,Daniele Cusi,Richard P. Lifton,Ali G. Gharavi +91 more
TL;DR: A genome-wide association study of IgA nephropathy (IgAN), the most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals of European and East Asian ancestry is performed, suggesting a possible role for host–intestinal pathogen interactions in shaping the genetic landscape of IgAN.
Journal ArticleDOI
Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis
Krzysztof Kiryluk,Yifu Li,Simone Sanna-Cherchi,Simone Sanna-Cherchi,Mersedeh Rohanizadegan,Hitoshi Suzuki,Frank Eitner,Holly J. Snyder,Murim Choi,Ping Hou,Francesco Scolari,Claudia Izzi,Maddalena Gigante,Loreto Gesualdo,Silvana Savoldi,Antonio Amoroso,Daniele Cusi,Pasquale Zamboli,Bruce A. Julian,Jan Novak,Robert J. Wyatt,Robert J. Wyatt,Krzysztof Mucha,Markus Perola,Markus Perola,Markus Perola,Kati Kristiansson,Alexander Viktorin,Patrik K. E. Magnusson,Gudmar Thorleifsson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Anne Boland,Marie Metzger,Lise Thibaudin,Christoph Wanner,Kitty J Jager,Shin Goto,Dita Maixnerova,Hussein H. Karnib,Judit Nagy,Ulf Panzer,Jingyuan Xie,Nan Chen,Vladimir Tesar,Ichiei Narita,François Berthoux,Juergen Floege,Bénédicte Stengel,Hong Zhang,Richard P. Lifton,Ali G. Gharavi +54 more
TL;DR: Variation at IgAN susceptibility loci correlates with differences in disease prevalence among world populations and inform genetic, biological, and epidemiological investigations of IgAN and permit cross-comparison with other complex traits that share genetic risk loci and geographic patterns with IgAN.
Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis
Krzysztof Kiryluk,Yifu Li,Simone Sanna-Cherchi,Simone Sanna-Cherchi,Mersedeh Rohanizadegan,Hitoshi Suzuki,Frank Eitner,Holly J. Snyder,Murim Choi,Ping Hou,Francesco Scolari,Claudia Izzi,Maddalena Gigante,Loreto Gesualdo,Silvana Savoldi,Antonio Amoroso,Daniele Cusi,Pasquale Zamboli,Bruce A. Julian,Jan Novak,Robert J. Wyatt,Robert J. Wyatt,Krzysztof Mucha,Markus Perola,Markus Perola,Markus Perola,Kati Kristiansson,Alexander Viktorin,Patrik K. E. Magnusson,Gudmar Thorleifsson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Anne Boland,Marie Metzger,Lise Thibaudin,Christoph Wanner,Kitty J Jager,Shin Goto,Dita Maixnerova,Hussein H. Karnib,Judit Nagy,Ulf Panzer,Jingyuan Xie,Nan Chen,Vladimir Tesar,Ichiei Narita,François Berthoux,Juergen Floege,Bénédicte Stengel,Hong Zhang,Richard P. Lifton,Ali G. Gharavi +54 more
TL;DR: In this article, the authors localized five IgAN susceptibility loci on Chr.6p21 (HLA-DQB1/DRB1, PSMB9/TAP1, and DPA1/DPB2 loci), Chr.1q32 (CFHR3/R1 locus), and Chr.22q12 (HORMAD2 locus) and tested association of these loci in eight new independent cohorts of Asian, European, and African-American ancestry.
Journal ArticleDOI
A nationwide blood spot screening study for Fabry disease in the Czech Republic haemodialysis patient population
Miroslav Merta,Jana Reiterova,Jana Ledvinová,Helena Poupětová,Robert Dobrovolný,Romana Rysava,Dita Maixnerova,Jan Bultas,Jiří Motáň,Jitka Slivkova,Doris Sobotova,Jana Smrzova,Vladimír Tesař +12 more
TL;DR: Blood spot screening (BSS) represents a promising screening tool that has proven to be convenient and effective in uncovering unrecognized FD patients among the chronic HD population in Czech Republic.
Journal ArticleDOI
Is there long-term value of pathology scoring in immunoglobulin A nephropathy? A validation study of the Oxford Classification for IgA Nephropathy (VALIGA) update
Rosanna Coppo,Graziella D'Arrigo,Giovanni Tripepi,Maria Luisa Russo,Ian S.D. Roberts,Shubha Bellur,Daniel C. Cattran,Terence Cook,John Feehally,Vladimir Tesar,Dita Maixnerova,Licia Peruzzi,Alessandro Amore,Sigrid Lundberg,Anna Maria Di Palma,Loreto Gesualdo,Francesco Emma,Cristiana Rollino,Manuel Praga,Luigi Biancone,Antonello Pani,Sandro Feriozzi,Rosaria Polci,Jonathan Barratt,Lucia Del Vecchio,Francesco Locatelli,Alessandro Pierucci,Yasar Caliskan,Agnieszka Perkowska-Ptasińska,Magdalena Durlik,Elisabetta Moggia,J. Ballarin,Jack F.M. Wetzels,Dimitris Goumenos,Marios Papasotiriou,Krešimir Galešić,Luka Toric,Aikaterini Papagianni,Maria Stangou,Luisa Benozzi,Stefano Cusinato,Ulla Berg,Rezan Topaloglu,Milena Maggio,Mai Ots-Rosenberg,Marco D'Amico,Colin C. Geddes,Olga Balafa,Marco Quaglia,Raffaella Cravero,Calogero Cirami,Bengt Fellström,Jürgen Floege,Jesús Egido,Francesca Mallamaci,Carmine Zoccali +55 more
TL;DR: Long-term follow-up analyses of the VALIGA cohort showed that the independent relationship between kidney biopsy findings and the risk of progression towards kidney failure in IgAN remains unchanged across all age groups and decades after the renal biopsy.