Sneh Lata

TL;DR: A genome-wide association study of IgA nephropathy (IgAN), the most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals of European and East Asian ancestry is performed, suggesting a possible role for host–intestinal pathogen interactions in shaping the genetic landscape of IgAN.

TL;DR: There is preference for certain residues at N and C termini, which helps to demarcate them from non-antibacterial peptides, which the authors hope will prove to be a boon to combat the dreadful antibiotic resistant bacteria.

TL;DR: Among antibacterial peptides, there is preference for certain residues at N and C terminus, which helps to discriminate them from non-antibacterial peptide and their further classification in source and family is studied.

TL;DR: Whole-exome sequencing is a genome-wide testing approach that allows selective sequencing of the protein-coding regions of the genome, which are enriched for disease-associated variants and is emerging as a preferred diagnostic tool for hereditary disorders.

TL;DR: ARID1A is identified as a novel tumor-suppressor gene in BE pathogenesis, reiterating the importance of aberrant chromatin in the metaplasia–dysplasia sequence and establishing the feasibility of using mucosal biopsies for NGS, which should enable the comparative analysis of larger ‘progressor’ versus ‘non-progressor' cohorts.