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Eric J. Topol
Researcher at Scripps Health
Publications - 1406
Citations - 162373
Eric J. Topol is an academic researcher from Scripps Health. The author has contributed to research in topics: Myocardial infarction & Angioplasty. The author has an hindex of 193, co-authored 1373 publications receiving 151025 citations. Previous affiliations of Eric J. Topol include Loyola University Chicago & Cleveland Clinic.
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Journal ArticleDOI
A randomized pilot trial of brief versus prolonged heparin after successful reperfusion in acute myocardial infarction.
TL;DR: In low-risk patients after successful reperfusion, prolonged heparin therapy does not protect against rethrombosis and is associated with a significantly higher rate of bleeding complications.
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Predictors of left ventricular function after acute myocardial infarction: effects of time to treatment, patency, and body mass index: the GUSTO-I angiographic experience
Conor F. Lundergan,Allan M. Ross,William F. McCarthy,Jonathan S. Reiner,Deneane Boyle,Cynthia Fink,Robert M. Califf,Eric J. Topol,Maarten L. Simoons,Marcel Van Den Brand,Frans Van de Werf,Karin S. Coyne +11 more
TL;DR: The ventricular function benefits of early complete reperfusion after myocardial infarction are readily demonstrable after adjustment for multiple covariables and include maintenance of global ventricularfunction and prevention or delay in ventricular dilatation.
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Antiplatelet and anticoagulant therapy in the secondary prevention of ischemic heart disease
Deepak L. Bhatt,Eric J. Topol +1 more
TL;DR: Antiplatelet and anticoagulant medications play a major role in the secondary prevention of ischemic heart disease and much remains to be learned about the merits of these different drug classes, relative to one another and in combination.
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An invasive strategy is associated with decreased mortality in patients with unstable angina and non–ST-elevation myocardial infarction: GUSTO IIb trial
Leslie Cho,Deepak L. Bhatt,S. Marso,Danielle M. Brennan,David R. Holmes,Robert M. Califf,Eric J. Topol +6 more
TL;DR: In patients presenting with acute coronary syndromes, an invasive strategy is associated with improved survival at 1 year even after adjusting for baseline differences, and in patients with unstable angina and non-ST-elevation myocardial infarction, a conservative strategy is related with lower 1-year mortality.