Eric J. Topol

TL;DR: The procedural outcome of directional coronary atherectomy is highly associated with coronary stenosis morphology, and after appropriate stratification for morphology and clinical presentation, overall atheresctomy procedural outcome may be similar to that achieved with coronary angioplasty.

TL;DR: In the thrombolytic era, AVB in the setting of STEMI is common and associated with higher mortality, and future studies should focus on determining therapies that are effective at reducing mortality rates in such patients.

TL;DR: Evaluated left ventricular regional wall motion by the centerline chord method in 332 patients treated with intravenous tissue-type plasminogen activator in the multicenter Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) I trial and revealed the most powerful clinical factor associated with enhanced function of the noninfarct zone was the absence of multivessel disease.

TL;DR: TSP-4 is expressed by vascular cells and influences the vessel wall by modulating the proliferation of ECs and smooth muscle cells, and the A387P substitution is a “gain-of-function” mutation that may be proatherogenic.

TL;DR: The objective of this paper is to describe the data privacy and security concerns that translational researchers need to be aware of, and discuss the tools and techniques available to them to help minimize that risk.