Eric J. Topol

TL;DR: Compared with heparin with or without GP IIb/IIIa inhibition, the use of bivalirudin in a large consecutive patient registry at a tertiary care center was associated with fewer bleeding events and no evident increase in the incidence of ischemic complications.

TL;DR: A 53-year-old man with occlusion of the proximal left anterior descending coronary artery received intravenous tissue plasminogen activator, and reperfusion was achieved within four and a half hours from the onset of chest pain, and autopsy demonstrated a massive hemorrhagic infarct.

TL;DR: This retrospective cohort study examined the hypothesis that shorter sleep duration and greater dayto-day variability of sleep duration are associated with increased body mass index (BMI).

TL;DR: Patients receiving fibrinolytic therapy for acute MI treatment in hospitals without coronary revascularization capability appear to have outcomes similar to those of patients admitted to hospitals with such capability when aspirin and beta-adrenergic blocking agents are given appropriately and transfer is available for angiography and angioplasty as needed.

TL;DR: The feasibility and safety of angioplasty after thrombolytic therapy are demonstrated and it is concluded that failure to improve ventricular function could be related both to the prolonged ischemic interval and the high-grade residual stenoses present after therapy.