Eric J. Topol

TL;DR: As racially mediated biologic differences between black and white patients become better understood, targeted interventions to prevent coronary heart disease and treat acute coronary syndromes in black patients can be developed.

TL;DR: Patients with healed myocardial infarction should be educated to ensure early hospital admission if they develop symptoms suggestive of acute infarctions, and upon hospital arrival should be promptly triaged to receive reperfusion therapy with accelerated alteplase.

TL;DR: The convergence of smartphone-enabled mobile computational and connectivity capabilities is only one aspect of digital medicine; it also encompasses genomics, information systems, wireless sensors, cloud computing, and machine learning that can all be incorporated into new systems of health management, built around realworld, patient-generated data.

TL;DR: The present study examines the tiistopathologic characteristics of the “culprit lesion” obtained during directional coronary atherectomy of patients with acute coronary syndromes, a unique opportunity for studying the composition of unstable lesions in living symptomatic patients.

TL;DR: Bivalirudin with provisional GPIIb/IIIa inhibitor use in low-risk ACS patients (not receiving preprocedural GPIIB/ IIIa blockade) appears to provide similar protection against death and myocardial infarction as the combination of heparin and GPIIa-IIIa inhibitors, although the authors observed a higher rate of revascularization at 6 months.