Eric J. Topol

TL;DR: In 1960, Lusted predicted an electronic scannercomputer to examine chest photofluorograms, to separate the clearly normal chest films from the abnormal chest films, and nearly 60 years after Lusted’s prediction, Enlitic, a technology company in Silicon Valley, inputted images of normal radiographs and radiographs with fractures into a computerized database.

TL;DR: It is now evident that the platelet is in fact a key mediator of thrombosis as well as of inflammation, and new insights at the cellular and genomic levels will probably generate novel drugs to inhibit platelet function more effectively and safely than previously possible.

TL;DR: Within the range currently considered to be normal, the risk for coronary disease rises with increasing plasma homocysteine regardless of age and sex, with no threshold effect.

TL;DR: In this paper, the authors characterized the contemporary relation between diabetes and outcome after myocardial infarction treated with thrombolytic agents from a large international cohort and found that patients with diabetes alone and in association with its comorbidities, portends a substantially worse 30-day and 1-year prognosis for patients with myocardious infarctions.

TL;DR: This review focuses on providing the clinically relevant biology of these families of adhesion molecules, setting the foundation for delineation of their emerging role in cardiovascular therapeutics.