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Eric J. Topol

Researcher at Scripps Health

Publications -  1406
Citations -  162373

Eric J. Topol is an academic researcher from Scripps Health. The author has contributed to research in topics: Myocardial infarction & Angioplasty. The author has an hindex of 193, co-authored 1373 publications receiving 151025 citations. Previous affiliations of Eric J. Topol include Loyola University Chicago & Cleveland Clinic.

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Abciximab reduces mortality in diabetics following percutaneous coronary intervention.

TL;DR: Abciximab therapy should be strongly considered in diabetic patients undergoing PCI to improve their survival and is noteworthy in those diabetic patients who are also hypertensive and obese and in diabetics undergoing multivessel intervention.
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Analysis of risk of bleeding complications after different doses of aspirin in 192,036 patients enrolled in 31 randomized controlled trials.

TL;DR: Findings should be considered when using combination antiplatelets, anticoagulant therapy, or both, with ASA, especially with the daily dose of >100 mg, despite substantial differences in the reporting patterns of bleeding complications.
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Troponin T Levels in Patients with Acute Coronary Syndromes, with or without Renal Dysfunction

TL;DR: Cardiac troponin T levels predict short-term prognosis in patients with acute coronary syndromes regardless of their level of creatinine clearance, and was independently predictive of risk across the entire spectrum of renal function.
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Predictors and impact of major hemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 Trial.

TL;DR: In this paper, the impact of major hemorrhage and its impact on mortality in patients undergoing elective or urgent PCI randomly assigned to heparin plus planned glycoprotein IIb/IIIa inhibitor versus bivalirudin plus provisional GPIs in the REPLACE-2 Trial were determined.
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Stroke After Thrombolysis Mortality and Functional Outcomes in the GUSTO-I Trial

TL;DR: In this paper, the authors analyzed the incidence, timing, and outcomes of stroke in an international trial and found that 1.4% of the patients had a stroke (93% anatomic documentation) and the risk ranged from 1.19% with streptokinase/subcutaneous heparin therapy to 1.64% with combination thrombolytic therapy.