E
Erik Ingelsson
Researcher at Stanford University
Publications - 546
Citations - 99427
Erik Ingelsson is an academic researcher from Stanford University. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 124, co-authored 538 publications receiving 85407 citations. Previous affiliations of Erik Ingelsson include Karolinska Institutet & Cardiovascular Institute of the South.
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Journal ArticleDOI
Genotype–covariate interaction effects and the heritability of adult body mass index
Matthew R. Robinson,Matthew R. Robinson,Geoffrey English,Gerhard Moser,Luke R. Lloyd-Jones,Marcus A. Triplett,Zhihong Zhu,Ilja M. Nolte,Jana V. van Vliet-Ostaptchouk,Harold Snieder,Tõnu Esko,Lili Milani,Reedik Mägi,Andres Metspalu,Patrik K. E. Magnusson,Nancy L. Pedersen,Erik Ingelsson,Erik Ingelsson,Magnus Johannesson,Jian Yang,David Cesarini,Peter M. Visscher +21 more
TL;DR: Estimating heritability for body mass index (BMI) in 172,000 sibling pairs and 150,832 unrelated individuals and exploring the contribution of genotype–covariate interaction effects at common SNP loci suggest that the genetic architecture of BMI is highly polygenic.
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Prevalence and Prognostic Impact of Subclinical Cardiovascular Disease in Individuals With the Metabolic Syndrome and Diabetes
Erik Ingelsson,Lisa M. Sullivan,Joanne M. Murabito,Caroline S. Fox,Emelia J. Benjamin,Joseph F. Polak,James B. Meigs,Michelle J. Keyes,Christopher J. O'Donnell,Christopher J. O'Donnell,Thomas J. Wang,Ralph B. D'Agostino,Philip A. Wolf,Ramachandran S. Vasan,Ramachandran S. Vasan +14 more
TL;DR: In this community-based sample, individuals with MetS have a high prevalence of subclinical atherosclerosis that likely contributes to the increased risk of overt CVD associated with the condition.
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Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
Jennifer L. Bolton,Caroline Hayward,Nese Direk,John G. Lewis,Geoffrey L. Hammond,Lesley A. Hill,Anna Anderson,Jennifer E. Huffman,James F. Wilson,Harry Campbell,Igor Rudan,Alan F. Wright,Nicholas D. Hastie,Sarah H. Wild,Fleur P. Velders,Albert Hofman,André G. Uitterlinden,Jari Lahti,Katri Räikkönen,Eero Kajantie,Elisabeth Widen,Aarno Palotie,Johan G. Eriksson,Marika Kaakinen,Marjo-Riitta Järvelin,Nicholas J. Timpson,George Davey Smith,Susan M. Ring,David M. Evans,Beate St Pourcain,Toshiko Tanaka,Yuri Milaneschi,Yuri Milaneschi,Stefania Bandinelli,Luigi Ferrucci,Pim van der Harst,Judith G. M. Rosmalen,Stephen J. L. Bakker,Niek Verweij,Robin P. F. Dullaart,Anubha Mahajan,Cecilia M. Lindgren,Andrew P. Morris,Lars Lind,Erik Ingelsson,Laura N. Anderson,Craig E. Pennell,Stephen J. Lye,Stephen G. Matthews,Joel Eriksson,Dan Mellström,Claes Ohlsson,Jackie F. Price,Mark W. J. Strachan,Rebecca M. Reynolds,Henning Tiemeier,Brian R. Walker +56 more
TL;DR: Findings reveal a novel common genetic source of variation in binding of cortisol by CBG, and reinforce the key role of CBG in determining plasma cortisol levels, and may contribute to cortisol-associated degenerative diseases.
Journal ArticleDOI
Novel metabolic risk factors for heart failure.
Erik Ingelsson,Johan Ärnlöv,Johan Sundström,Björn Zethelius,Bengt Vessby,Lars Lind,Lars Lind +6 more
TL;DR: Novel variables reflecting insulin resistance and dyslipidemia, together with a low beta-carotene level, were found to predict HF independently of established risk factors.
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Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease
TL;DR: In this article, the effect of antileukotriene receptor antagonist montelukast on future risk of incident and recurrent myocardial infarction and ischemic stroke was examined.