E
Erik Ingelsson
Researcher at Stanford University
Publications - 546
Citations - 99427
Erik Ingelsson is an academic researcher from Stanford University. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 124, co-authored 538 publications receiving 85407 citations. Previous affiliations of Erik Ingelsson include Karolinska Institutet & Cardiovascular Institute of the South.
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Journal ArticleDOI
Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry
Jennifer A. Nettleton,Jack L. Follis,Julius S. Ngwa,Caren E. Smith,Shafqat Ahmad,Toshiko Tanaka,Mary K. Wojczynski,Trudy Voortman,Rozenn N. Lemaitre,Kati Kristiansson,Marja-Liisa Nuotio,Denise K. Houston,Mia-Maria Perälä,Qibin Qi,Emily Sonestedt,Ani Manichaikul,Stavroula Kanoni,Andrea Ganna,Vera Mikkilä,Kari E. North,David S. Siscovick,Kennet Harald,Nicola M. McKeown,Ingegerd Johansson,Harri Rissanen,Yongmei Liu,Jari Lahti,Frank B. Hu,Stefania Bandinelli,Gull Rukh,Stephen S. Rich,Lisanne Booij,Maria Dmitriou,Erika Ax,Olli T. Raitakari,Kenneth J. Mukamal,Satu Männistö,Göran Hallmans,Antti Jula,Ulrika Ericson,David R. Jacobs,Frank J. A. van Rooij,Panos Deloukas,Per Sjögren,Mika Kähönen,Luc Djoussé,Markus Perola,Inês Barroso,Albert Hofman,Kathleen Stirrups,Jorma Viikari,André G. Uitterlinden,Ioanna P. Kalafati,Oscar H. Franco,Dariush Mozaffarian,Veikko Salomaa,Ingrid B. Borecki,Paul Knekt,Stephen B. Kritchevsky,Johan G. Eriksson,George Dedoussis,Lu Qi,Luigi Ferrucci,Marju Orho-Melander,M. Carola Zillikens,Erik Ingelsson,Terho Lehtimäki,Frida Renström,L. Adrienne Cupples,Ruth J. F. Loos,Paul W. Franks,Paul W. Franks +71 more
TL;DR: Ass associations between genetic predisposition and obesity traits were stronger with a healthier diet, and diet score modification of genetic associations with BMI and BMI-adjusted WHR was identified.
Journal ArticleDOI
Global DNA hypermethylation is associated with high serum levels of persistent organic pollutants in an elderly population.
Lars Lind,Johanna Penell,Karin Luttropp,Louise Nordfors,Anne-Christine Syvänen,Tomas Axelsson,Samira Salihovic,Bert van Bavel,Tove Fall,Erik Ingelsson,P. Monica Lind +10 more
TL;DR: In a sample of elderly subjects, high TEQ including PCBs and the dioxin OCDD and high serum levels of PCB126, OCDD, and p,p'-DDE were related to global DNA hypermethylation in a cross-sectional analysis.
Journal ArticleDOI
Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts
Christoph Nowak,Johan Sundström,Stefan Gustafsson,Vilmantas Giedraitis,Lars Lind,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Tove Fall +8 more
TL;DR: Proteomic blood profiling indicated cathepsin D as a new IR biomarker and suggested a causal effect of IR on t-PA, which was associated with incident T2D and predicted 5-year transition to hyperglycemia.
Journal ArticleDOI
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
Anubha Mahajan,Xueling Sim,Hui Jin Ng,Alisa K. Manning,Manuel A. Rivas,Heather M. Highland,Adam E. Locke,Niels Grarup,Hae Kyung Im,Pablo Cingolani,Jason Flannick,Pierre Fontanillas,Christian Fuchsberger,Kyle J. Gaulton,Tanya M. Teslovich,N. William Rayner,Neil R. Robertson,Nicola L. Beer,Jana K. Rundle,Jette Bork-Jensen,Claes Ladenvall,Christine Blancher,David Buck,Gemma Buck,Noël P. Burtt,Stacey Gabriel,Anette P. Gjesing,Christopher J. Groves,Mette Hollensted,Jeroen R. Huyghe,Anne U. Jackson,Goo Jun,Johanne Marie Justesen,Massimo Mangino,Jacquelyn Murphy,Matt J. Neville,Robert C. Onofrio,Kerrin S. Small,Heather M. Stringham,Ann-Christine Syvänen,Joseph Trakalo,Gonçalo R. Abecasis,Graeme I. Bell,John Blangero,Nancy J. Cox,Ravindranath Duggirala,Craig L. Hanis,Mark Seielstad,James G. Wilson,Cramer Christensen,Ivan Brandslund,Rainer Rauramaa,Gabriela L. Surdulescu,Alex S. F. Doney,Lars Lannfelt,Allan Linneberg,Bo Isomaa,Tiinamaija Tuomi,Marit E. Jørgensen,Torben Jørgensen,Johanna Kuusisto,Matti Uusitupa,Veikko Salomaa,Tim D. Spector,Andrew D. Morris,Colin N. A. Palmer,Francis S. Collins,Karen L. Mohlke,Richard N. Bergman,Erik Ingelsson,Lars Lind,Jaakko Tuomilehto,Torben Hansen,Richard M. Watanabe,Inga Prokopenko,Josée Dupuis,Fredrik Karpe,Leif Groop,Markku Laakso,Oluf Pedersen,Jose C. Florez,Andrew P. Morris,David Altshuler,James B. Meigs,Michael Boehnke,Mark I. McCarthy,Cecilia M. Lindgren,Anna L. Gloyn +87 more
TL;DR: In this article, the authors analyzed exome-array data from up to 33,231 non-diabetic individuals of European ancestry and identified multiple coding variants in G6PC2 (p.Val219Leu, p.His177Tyr, and p.Tyr207Ser) influencing FG levels, conditionally independent of each other and the non-coding GWAS signal.
Journal ArticleDOI
Circulating proteins as predictors of incident heart failure in the elderly
Markus Stenemo,Christoph Nowak,Liisa Byberg,Johan Sundström,Vilmantas Giedraitis,Lars Lind,Erik Ingelsson,Erik Ingelsson,Tove Fall,Johan Ärnlöv,Johan Ärnlöv +10 more
TL;DR: To identify novel risk markers for incident heart failure using proteomic profiling of 80 proteins previously associated with cardiovascular pathology, a large number of the proteins have been known to be involved in heart failure.