E
Erik Ingelsson
Researcher at Stanford University
Publications - 546
Citations - 99427
Erik Ingelsson is an academic researcher from Stanford University. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 124, co-authored 538 publications receiving 85407 citations. Previous affiliations of Erik Ingelsson include Karolinska Institutet & Cardiovascular Institute of the South.
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The Trans-Ancestral Genomic Architecture of Glycaemic Traits
Ji Chen,Ji Chen,Cassandra N. Spracklen,Cassandra N. Spracklen,Gaëlle Marenne,Gaëlle Marenne,Arushi Varshney,Laura J Corbin,Jian'an Luan,Sara M. Willems,Ying Wu,Xiaoshuai Zhang,Xiaoshuai Zhang,Momoko Horikoshi,Thibaud S. Boutin,Reedik Mägi,Johannes Waage,Johannes Waage,Achilleas Pitsilides,Ruifang Li-Gao,Kei Hang,Kei Hang,Jie Yao,Mila Desi Anasanti,Audrey Y. Chu,Annique Claringbould,Jani Heikkinen,Jaeyoung Hong,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Shaofeng Huo,Marika Kaakinen,Marika Kaakinen,Tin Louie,Winfried März,Winfried März,Winfried März,Hortensia Moreno-Macías,Anne Ndungu,Sarah C. Nelson,Ilja M. Nolte,Kari E. North,Chelsea K. Raulerson,Debashree Ray,Rebecca Rohde,Denis Rybin,Claudia Schurmann,Claudia Schurmann,Xueling Sim,Xueling Sim,L. Southam,Isobel D. Stewart,Carol A. Wang,Yujie Wang,Peitao Wu,Weihua Zhang,Weihua Zhang,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Emil V. R. Appel,Lawrence F. Bielak,Jennifer A. Brody,Noël P. Burtt,Claudia P. Cabrera,Brian E. Cade,Brian E. Cade,Jin Fang Chai,Xiaoran Chai,Li-Ching Chang,Chien-Hsiun Chen,Brian H. Chen,Kumaraswamy Naidu Chitrala,Yen-Feng Chiu,Hugoline G. de Haan,Graciela E. Delgado,Ayse Demirkan,Qing Duan,Jorgen Engmann,Segun Fatumo,Javier Gayán,Franco Giulianini,Jung Ho Gong,Stefan Gustafsson,Yang Hai,Fernando Pires Hartwig,Fernando Pires Hartwig,Jing He,Yoriko Heianza,Tao Huang,Alicia Huerta-Chagoya,Mi Yeong Hwang,Richard A. Jensen,Takahisa Kawaguchi,Katherine A. Kentistou,Young-Jin Kim,Marcus E. Kleber,Ishminder K. Kooner,Shuiqing Lai,Leslie A. Lange,Carl D. Langefeld,Marie Lauzon,Man Li,Symen Ligthart,Jun Liu,Jun Liu,Marie Loh,Marie Loh,Jirong Long,Valeriya Lyssenko,Valeriya Lyssenko,Massimo Mangino,Carola Marzi,May E. Montasser,Abhishek Nag,Masahiro Nakatochi,Damia Noce,Raymond Noordam,Giorgio Pistis,Michael Preuss,Laura M. Raffield,Laura J. Rasmussen-Torvik,Stephen S. Rich,Neil R. Robertson,Rico Rueedi,Rico Rueedi,Kathleen A. Ryan,Serena Sanna,Richa Saxena,Richa Saxena,Katharina E. Schraut,Bengt Sennblad,Kazuya Setoh,Albert V. Smith,Lorraine Southam,Thomas Sparsø,Rona J. Strawbridge,Rona J. Strawbridge,Fumihiko Takeuchi,Jingyi Tan,Stella Trompet,Erik B. van den Akker,Erik B. van den Akker,Peter J. van der Most,Niek Verweij,Mandy Vogel,Heming Wang,Chaolong Wang,Chaolong Wang,Nan Wang,Helen R. Warren,Wanqing Wen,Tom Wilsgaard,Andrew Wong,Andrew R. Wood,Tian Xie,Mohammad Hadi Zafarmand,Jing Hua Zhao,Wei Zhao,Najaf Amin,Zorayr Arzumanyan,Arne Astrup,Stephan J. L. Bakker,Damiano Baldassarre,Marian Beekman,Richard N. Bergman,Alain G. Bertoni,Matthias Blüher,Lori L. Bonnycastle,Stefan R. Bornstein,Donald W. Bowden,Qiuyin Cai,Archie Campbell,Archie Campbell,Harry Campbell,Yi-Cheng Chang,Eco J. C. de Geus,Eco J. C. de Geus,Abbas Dehghan,Shufa Du,Gudny Eiriksdottir,Aliki-Eleni Farmaki,Aliki-Eleni Farmaki,Mattias Frånberg,Christian Fuchsberger,Yu-Tang Gao,Anette P. Gjesing,Anuj Goel,Sohee Han,Catharina A. Hartman,Christian Herder,Andrew A. Hicks,Chang-Hsun Hsieh,Chang-Hsun Hsieh,Willa A. Hsueh,Sahoko Ichihara,Michiya Igase,M. Arfan Ikram,W. Craig Johnson,Marit E. Jørgensen,Marit E. Jørgensen,Peter K. Joshi,Rita R. Kalyani,Fouad Kandeel,Tomohiro Katsuya,Chiea Chuen Khor,Wieland Kiess,Ivana Kolcic,Teemu Kuulasmaa,Johanna Kuusisto,Kristi Läll,Kelvin Lam,Debbie A Lawlor,Nanette R. Lee,Rozenn N. Lemaitre,Honglan Li,Shih-Yi Lin,Jaana Lindström,Allan Linneberg,Allan Linneberg,Jianjun Liu,Jianjun Liu,Carlos Lorenzo,Tatsuaki Matsubara,Fumihiko Matsuda,Geltrude Mingrone,Simon P. Mooijaart,Sanghoon Moon,Toru Nabika,Girish N. Nadkarni,Jerry L. Nadler,Mari Nelis,Matt J. Neville,Jill M. Norris,Yasumasa Ohyagi,Annette Peters,Patricia A. Peyser,Ozren Polasek,Qibin Qi,Dennis Raven,Dermot F. Reilly,Alexander P. Reiner,Fernando Rivideneira,Kathryn Roll,Igor Rudan,Charumathi Sabanayagam,Kevin Sandow,Naveed Sattar,Annette Schürmann,Shi Jinxiu,Heather M. Stringham,Kent D. Taylor,Tanya M. Teslovich,Betina H. Thuesen,Paul R. H. J. Timmers,Elena Tremoli,Michael Y. Tsai,André G. Uitterlinden,Rob M. van Dam,Rob M. van Dam,Diana van Heemst,Astrid van Hylckama Vlieg,Jana V. van Vliet-Ostaptchouk,Jagadish Vangipurapu,Henrik Vestergaard,Henrik Vestergaard,Tao Wang,Ko Willems van Dijk,Yong-Bing Xiang,Tatijana Zemunik,Gonçalo R. Abecasis,Linda S. Adair,Carlos A. Aguilar-Salinas,Marta E. Alarcón-Riquelme,Marta E. Alarcón-Riquelme,Ping An,Larissa Aviles-Santa,Diane M. Becker,Lawrence J. Beilin,Sven Bergmann,Sven Bergmann,Sven Bergmann,Hans Bisgaard,Hans Bisgaard,Corri Black,Michael Boehnke,Eric Boerwinkle,Eric Boerwinkle,Bernhard O. Böhm,Bernhard O. Böhm,Klaus Bønnelykke,Klaus Bønnelykke,D.I. Boomsma,D.I. Boomsma,Erwin P. Bottinger,Erwin P. Bottinger,Erwin P. Bottinger,Thomas A. Buchanan,Mickaël Canouil,Mickaël Canouil,Mark J. Caulfield,John C. Chambers,Daniel I. Chasman,Yii-Der Ida Chen,Ching-Yu Cheng,Francis S. Collins,Adolfo Correa,Francesco Cucca,H. Janaka de Silva,George Dedoussis,Sölve Elmståhl,Michele K. Evans,Ele Ferranni,Luigi Ferruci,Jose C. Florez,Jose C. Florez,Paul W. Franks,Timothy M. Frayling,Philippe Froguel,Philippe Froguel,Philippe Froguel,Bruna Gigante,Mark O. Goodarzi,Penny Gordon-Larsen,Harald Grallert,Niels Grarup,Sameline Grimsgaard,Leif Groop,Leif Groop,Vilmundur Gudnason,Xiuqing Guo,Anders Hamsten,Torben Hansen,Caroline Hayward,Susan R. Heckbert,Bernardo L. Horta,Wei Huang,Erik Ingelsson,Pankow S. James,Jost B. Jonas,Jost B. Jonas,J. Wouter Jukema,Pontiano Kaleebu,Robert C. Kaplan,Robert C. Kaplan,Sharon L.R. Kardia,Norihiro Kato,Sirkka Keinänen-Kiukaanniemi,Sirkka Keinänen-Kiukaanniemi,Bong-Jo Kim,Mika Kivimäki,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Jaspal S. Kooner,Antje Körner,Peter Kovacs,Diana Kuh,Meena Kumari,Zoltán Kutalik,Zoltán Kutalik,Markku Laakso,Timo A. Lakka,Lenore J. Launer,Karin Leander,Huaixing Li,Xu Lin,Lars Lind,Cecilia M. Lindgren,Simin Liu,Ruth J. F. Loos,Patrik K. E. Magnusson,Anubha Mahajan,Andres Metspalu,Dennis O. Mook-Kanamori,Trevor A. Mori,Patricia B. Munroe,Inger Njølstad,Jeffrey R. O'Connell,Albertine J. Oldehinkel,Ken K. Ong,Sandosh Padmanabhan,Colin N. A. Palmer,Nicholette D. Palmer,Oluf Pedersen,Craig E. Pennell,David J. Porteous,David J. Porteous,Peter P. Pramstaller,Michael A. Province,Bruce M. Psaty,Lu Qi,Leslie J. Raffel,Rainer Rauramaa,Susan Redline,Susan Redline,Paul M. Ridker,Frits R. Rosendaal,Timo Saaristo,Manjinder S. Sandhu,Jouko Saramies,Neil Schneiderman,Peter E. H. Schwarz,Peter E. H. Schwarz,Laura J. Scott,Elizabeth Selvin,Peter S. Sever,Xiao-Ou Shu,P. Eline Slagboom,Kerrin S. Small,Blair H. Smith,Harold Snieder,Tamar Sofer,Tamar Sofer,Thorkild I. A. Sørensen,Tim D. Spector,Alice Stanton,Claire J. Steves,Michael Stumvoll,Liang Sun,Yasuharu Tabara,E. Shyong Tai,Nicholas J. Timpson,Anke Tönjes,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,Teresa Tusie,Matti Uusitupa,Pim van der Harst,Cornelia M. van Duijn,Cornelia M. van Duijn,Veronique Vitart,Peter Vollenweider,Tanja G. M. Vrijkotte,Lynne E. Wagenknecht,Mark Walker,Ya X. Wang,Nicholas J. Wareham,Richard M. Watanabe,Hugh Watkins,Wen B. Wei,Ananda R. Wickremasinghe,Gonneke Willemsen,Gonneke Willemsen,James F. Wilson,Tien Yin Wong,Jer-Yuarn Wu,Anny H. Xiang,Lisa R. Yanek,Loic Yengo,Loic Yengo,Loic Yengo,Mitsuhiro Yokota,Eleftheria Zeggini,Eleftheria Zeggini,Wei Zheng,Alan B. Zonderman,Jerome I. Rotter,Anna L. Gloyn,Mark I. McCarthy,Josée Dupuis,James B. Meigs,James B. Meigs,Robert A. Scott,Inga Prokopenko,Inga Prokopenko,Aaron Leong,Ching-Ti Liu,Stephen C. J. Parker,Karen L. Mohlke,Claudia Langenberg,Eleanor Wheeler,Eleanor Wheeler,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Inês Barroso,Inês Barroso,Inês Barroso +478 more
TL;DR: Genomic feature, gene-expression and gene-set analyses revealed distinct biological signatures for each trait, highlighting different underlying biological pathways, increasing understanding of diabetes pathophysiology by use of trans-ancestry studies for improved power and resolution.
Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche
John R. B. Perry,Felix R. Day,Cathy E. Elks,Patrick Sulem,Deborah J. Thompson,Teresa Ferreira,Chunyan He,Daniel I. Chasman,Tõnu Esko,Gudmar Thorleifsson,Eva Albrecht,Wei Ang,Tanguy Corre,Diana L. Cousminer,Bjarke Feenstra,Nora Franceschini,Andrea Ganna,Andrew D. Johnson,Sanela Kjellqvist,Kathryn L. Lunetta,George McMahon,Ilja M. Nolte,Lavinia Paternoster,Eleonora Porcu,Albert V. Smith,Lisette Stolk,Alexander Teumer,Natalia Tšernikova,Emmi Tikkanen,Sheila Ulivi,Erin K. Wagner,Najaf Amin,Laura J. Bierut,Enda M. Byrne,Jouke-Jan Hottenga,Daniel L. Koller,Massimo Mangino,Tune H. Pers,Laura M. Yerges-Armstrong,Jing Hua Zhao,Irene L. Andrulis,Hoda Anton-Culver,Femke Atsma,Stefania Bandinelli,Matthias W. Beckmann,Javier Benitez,Carl Blomqvist,Stig E. Bojesen,Manjeet K. Bolla,Bernardo Bonanni,Hiltrud Brauch,Hermann Brenner,Julie E. Buring,Jenny Chang-Claude,Stephen J. Chanock,Jinhui Chen,Georgia Chenevix-Trench,J. Margriet Collée,Fergus J. Couch,David Couper,Andrea D. Coveillo,Angela Cox,Kamila Czene,Adamo Pio d'Adamo,George Davey Smith,Immaculata De Vivo,Ellen W. Demerath,Joe Dennis,Peter Devilee,Aida Karina Dieffenbach,Alison M. Dunning,Gudny Eiriksdottir,Johan G. Eriksson,Peter A. Fasching,Luigi Ferrucci,Dieter Flesch-Janys,Henrik Flyger,Tatiana Foroud,Lude Franke,Melissa E. Garcia,Montserrat Garcia-Closas,Frank Geller,Eco de Geus,Graham G. Giles,Daniel F. Gudbjartsson,Vilmundur Gudnason,Pascal Guénel,Suiqun Guo,Per Hall,Ute Hamann,Robin Haring,Catharina A. Hartman,Andrew Heath,Albert Hofman,Maartje J. Hooning,John L. Hopper,Frank B. Hu,David J. Hunter,David Karasik,Douglas P. Kiel,Julia A. Knight,Veli-Matti Kosma,Zoltán Kutalik,Sandra Lai,Diether Lambrechts,Annika Lindblom,Reedik Mägi,Patrik K. E. Magnusson,Arto Mannermaa,Nicholas G. Martin,Gisli Masson,Patrick F. McArdle,Wendy L. McArdle,Mads Melbye,Kyriaki Michailidou,Evelin Mihailov,Lili Milani,Roger L. Milne,Heli Nevanlinna,Patrick Neven,Ellen A. Nohr,Albertine J. Oldehinkel,Ben A. Oostra,Aarno Palotie,Munro Peacock,Nancy L. Pedersen,Paolo Peterlongo,Julian Peto,Paul D.P. Pharoah,Dirkje S. Postma,Anneli Pouta,Katri Pylkäs,Paolo Radice,Susan M. Ring,Fernando Rivadeneira,Antonietta Robino,Lynda M. Rose,Anja Rudolph,Veikko Salomaa,Serena Sanna,David Schlessinger,Marjanka K. Schmidt,Mellissa C. Southey,Ulla Sovio,Meir J. Stampfer,Doris Stöckl,Anna Maria Storniolo,Nicholas J. Timpson,Jonathan Tyrer,Jenny A. Visser,Peter Vollenweider,Henry Völzke,Gérard Waeber,Melanie Waldenberger,Henri Wallaschofski,Qin Wang,Gonneke Willemsen,Robert Winqvist,Bruce H. R. Wolffenbuttel,Margaret J. Wright,Dorret I. Boomsma,Michael J. Econs,Kay-Tee Khaw,Ruth J. F. Loos,Mark I. McCarthy,Grant W. Montgomery,John P. Rice,Elizabeth A. Streeten,Unnur Thorsteinsdottir,Cornelia M. van Duijn,Behrooz Z. Alizadeh,Sven Bergmann,Eric Boerwinkle,Heather A. Boyd,Laura Crisponi,Paolo Gasparini,Christian Gieger,Tamara B. Harris,Erik Ingelsson,Marjo-Riitta Järvelin,Peter Kraft,Debbie A Lawlor,Andres Metspalu,Craig E. Pennell,Paul M. Ridker,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,David P. Strachan,André G. Uitterlinden,Nicholas J. Wareham,Elisabeth Widen,Marek Zygmunt,Anna Murray,Douglas F. Easton,Kari Stefansson,Joanne M. Murabito,Ken K. Ong +197 more
Journal ArticleDOI
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Jayne F. Martin Carli,Alicja A. Skowronski,Qi Sun,Qi Sun,Jennifer Kriebel,Mary F. Feitosa,Åsa K. Hedman,Åsa K. Hedman,Åsa K. Hedman,Alexander W. Drong,James E. Hayes,James E. Hayes,Jing Hua Zhao,Tune H. Pers,Ursula M. Schick,Niels Grarup,Zoltán Kutalik,Zoltán Kutalik,Stella Trompet,Massimo Mangino,Massimo Mangino,Kati Kristiansson,Kati Kristiansson,Marian Beekman,Leo-Pekka Lyytikäinen,Joel Eriksson,Peter Henneman,Peter Henneman,Jari Lahti,Toshiko Tanaka,Jian'an Luan,Fabiola Del Greco M,Dorota Pasko,Frida Renström,Frida Renström,Sara M. Willems,Anubha Mahajan,Lynda M. Rose,Xiuqing Guo,Yongmei Liu,Marcus E. Kleber,Louis Pérusse,Tom R. Gaunt,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Yun Ju Sung,Yolande F. M. Ramos,Najaf Amin,Antoinette Amuzu,Inês Barroso,Inês Barroso,Claire Bellis,Claire Bellis,Claire Bellis,John Blangero,Brendan M. Buckley,Stefan Böhringer,Yii-Der Ida Chen,Anton J. N. de Craen,David R. Crosslin,Caroline Dale,Zari Dastani,Felix R. Day,Joris Deelen,Graciela E. Delgado,Ayse Demirkan,Ayse Demirkan,Francis M. Finucane,Ian Ford,Melissa E. Garcia,Christian Gieger,Stefan Gustafsson,Stefan Gustafsson,Göran Hallmans,Susan E. Hankinson,Susan E. Hankinson,Susan E. Hankinson,Aki S. Havulinna,Christian Herder,Dena G. Hernandez,Andrew A. Hicks,David J. Hunter,Thomas Illig,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Andrea Ioan-Facsinay,John-Olov Jansson,Nancy S. Jenny,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,Torben Jørgensen,Magnus Karlsson,Wolfgang Koenig,Wolfgang Koenig,Peter Kraft,J.C. Kwekkeboom,Tiina Laatikainen,Tiina Laatikainen,Karl-Heinz Ladwig,Charles A. LeDuc,Gordon D.O. Lowe,Yingchang Lu,Pedro Marques-Vidal,Christina Meisinger,Cristina Menni,Andrew P. Morris,Andrew P. Morris,Richard H. Myers,Satu Männistö,Mike A. Nalls,Lavinia Paternoster,Annette Peters,Aruna D. Pradhan,Aruna D. Pradhan,Tuomo Rankinen,Laura J. Rasmussen-Torvik,Wolfgang Rathmann,Treva Rice,J. Brent Richards,J. Brent Richards,Paul M. Ridker,Paul M. Ridker,Naveed Sattar,David B. Savage,Stefan Söderberg,Nicholas J. Timpson,Liesbeth Vandenput,Diana van Heemst,Hae-Won Uh,Marie-Claude Vohl,Mark Walker,Heinz-Erich Wichmann,Heinz-Erich Wichmann,Elisabeth Widen,Andrew R. Wood,Jie Yao,Tanja Zeller,Yiying Zhang,Ingrid Meulenbelt,Margreet Kloppenburg,Arne Astrup,Thorkild I. A. Sørensen,Mark A. Sarzynski,Dabeeru C. Rao,Pekka Jousilahti,Erkki Vartiainen,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,Eero Kajantie,Eero Kajantie,Eero Kajantie,Clive Osmond,Aarno Palotie,Aarno Palotie,Aarno Palotie,Johan G. Eriksson,Johan G. Eriksson,Markku Heliövaara,Paul Knekt,Seppo Koskinen,Antti Jula,Markus Perola,Markus Perola,Markus Perola,Risto Huupponen,Risto Huupponen,Jorma Viikari,Jorma Viikari,Mika Kähönen,Terho Lehtimäki,Olli T. Raitakari,Olli T. Raitakari,Dan Mellström,Mattias Lorentzon,Juan P. Casas,Stefania Bandinelli,Winfried März,Winfried März,Winfried März,Aaron Isaacs,Ko Willems van Dijk,Cornelia M. van Duijn,Tamara B. Harris,Claude Bouchard,Matthew A. Allison,Daniel I. Chasman,Daniel I. Chasman,Claes Ohlsson,Lars Lind,Robert A. Scott,Claudia Langenberg,Nicholas J. Wareham,Luigi Ferrucci,Timothy M. Frayling,Peter P. Pramstaller,Ingrid B. Borecki,Dawn M. Waterworth,Sven Bergmann,Sven Bergmann,Gérard Waeber,Peter Vollenweider,Henrik Vestergaard,Henrik Vestergaard,Torben Hansen,Torben Hansen,Oluf Pedersen,Frank B. Hu,P. Eline Slagboom,Harald Grallert,Tim D. Spector,Joop Jukema,Robert J. Klein,Eric E. Schadt,Paul W. Franks,Paul W. Franks,Paul W. Franks,Cecilia M. Lindgren,Cecilia M. Lindgren,Cecilia M. Lindgren,Rudolph L. Leibel,Ruth J. F. Loos,Ruth J. F. Loos +227 more
TL;DR: In this article, the authors performed a genome-wide association study (GWAS) of circulating leptin levels from 32,161 individuals and identified five loci robustly associated with leptin levels in/near LEP, SLC32A1, GCKR, CCNL1 and FTO.
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
Lisette Stolk,John R. B. Perry,Daniel I. Chasman,Chunyan He,Massimo Mangino,Patrick Sulem,Maja Barbalić,Linda Broer,Enda M. Byrne,Florian Ernst,Tõnu Esko,Nora Franceschini,Daniel F. Gudbjartsson,Jouke-Jan Hottenga,P. Kraft,Patrick F. McArdle,Eleonora Porcu,So-Youn Shin,Albert V. Smith,S. van Wingerden,Guangju Zhai,Wei V. Zhuang,Eva Albrecht,Behrooz Z. Alizadeh,Thor Aspelund,Stefania Bandinelli,Lovorka Barać Lauc,Jacques S. Beckmann,Mladen Boban,Eric Boerwinkle,Frank J.M. Broekmans,Andrea Burri,Harry Campbell,Stephen J. Chanock,Constance Chen,Marilyn C. Cornelis,Tanguy Corre,Andrea D. Coviello,Pio D'Adamo,Gail Davies,U de Faire,E.J.C. de Geus,Ian J. Deary,George Dedoussis,Panagiotis Deloukas,Shah Ebrahim,G. Eiriksdottir,Valur Emilsson,Johan G. Eriksson,B. C. Fauser,Liana Ferreli,Luigi Ferrucci,Krista Fischer,Aaron R. Folsom,Melissa E. Garcia,Paolo Gasparini,Christian Gieger,Nicole L. Glazer,D. E. Grobbee,Per Hall,T. Haller,Susan E. Hankinson,M. Hass,Caroline Hayward,A. C. Heath,Albert Hofman,Erik Ingelsson,A. C. J. W. Janssens,Andrew D. Johnson,David Karasik,Sharon L.R. Kardia,Jules J. Keyzer,Douglas P. Kiel,Ivana Kolcic,Zoltán Kutalik,Jari Lahti,Sandra Lai,Triin Laisk,Joop S.E. Laven,Debbie A Lawlor,Jianjun Liu,Lorna M. Lopez,Yvonne V. Louwers,Patrik K. E. Magnusson,Mara Marongiu,Nicholas G. Martin,Irena Martinović Klarić,Corrado Masciullo,Barbara McKnight,S. E. Medland,David Melzer,Vincent Mooser,Pau Navarro,Anne B. Newman,Dale R. Nyholt,N. C. Onland-Moret,Aarno Palotie,Guillaume Paré,Alex Parker,N. L. Pedersen,P. H. M. Peeters,Giorgio Pistis,Andrew S. Plump,Ozren Polasek,Victor J M Pop,Bruce M. Psaty,Katri Räikkönen,Emil Rehnberg,Jerome I. Rotter,Igor Rudan,Cinzia Sala,Andres Salumets,Angelo Scuteri,AB Singleton,Jennifer A. Smith,Harold Snieder,Nicole Soranzo,Simon N. Stacey,John M. Starr,Maria G. Stathopoulou,Kathy Stirrups,Ronald P. Stolk,Unnur Styrkarsdottir,Yan V. Sun,Albert Tenesa,Barbara Thorand,Daniela Toniolo,Laufey Tryggvadottir,Kim Tsui,S. Ulivi,R. M. van Dam,Y. T. van der Schouw,C. H. van Gils,P. van Nierop,Jacqueline M. Vink,Peter M. Visscher,Marlies Voorhuis,G. Waeber,Henri Wallaschofski,H. E. Wichmann,Elisabeth Widen,C. J. Wijnands-van Gent,Gonneke Willemsen,James F. Wilson,Bruce H. R. Wolffenbuttel,A. F. Wright,Laura M. Yerges-Armstrong,Tatijana Zemunik,Lina Zgaga,M. C. Zillikens,Marek Zygmunt,T. L. Study,Alice M. Arnold,Dorret I. Boomsma,Julie E. Buring,Laura Crisponi,Ellen W. Demerath,Vilmundur Gudnason,Tamara B. Harris,Frank B. Hu,David J. Hunter,Lenore J. Launer,Andres Metspalu,Grant W. Montgomery,Ben A. Oostra,Paul M. Ridker,Serena Sanna,David Schlessinger,Tim D. Spector,Kari Stefansson,Elizabeth A. Streeten,Unnur Thorsteinsdottir,Manuela Uda,André G. Uitterlinden,C M van Duijn,Henry Völzke,Anna Murray,Joanne M. Murabito,Jenny A. Visser,Kathryn L. Lunetta +179 more
TL;DR: A meta-analysis of genome-wide association studies in 38,968 women of European descent identified 13 loci newly associated with age at natural menopause, and candidate genes located at these newly associated loci include genes implicated in DNA repair and immune function.
Journal ArticleDOI
A Central Role for GRB10 in Regulation of Islet Function in Man.
Inga Prokopenko,Wenny Poon,Reedik Mägi,Rashmi Prasad B,S Albert Salehi,Peter Almgren,Peter Osmark,Nabila Bouatia-Naji,Nils Wierup,Tove Fall,Alena Stančáková,Adam Barker,Vasiliki Lagou,Clive Osmond,Weijia Xie,Jari Lahti,Anne U. Jackson,Yu-Ching Cheng,Jie Liu,Jeffrey R. O'Connell,Paul Blomstedt,João Fadista,Sami Alkayyali,Tasnim Dayeh,Emma Ahlqvist,Jalal Taneera,Cécile Lecoeur,Ashok Kumar,Ola Hansson,Karin M Hansson,Benjamin F. Voight,Hyun Min Kang,Claire Levy-Marchal,Vincent Vatin,Aarno Palotie,Ann-Christine Syvänen,Andrea Mari,Michael N. Weedon,Ruth J. F. Loos,Ken K. Ong,Peter M. Nilsson,Bo Isomaa,Tiinamaija Tuomi,Nicholas J. Wareham,Michael Stumvoll,Elisabeth Widen,Timo A. Lakka,Claudia Langenberg,Anke Tönjes,Rainer Rauramaa,Johanna Kuusisto,Timothy M. Frayling,Philippe Froguel,Mark Walker,Johan G. Eriksson,Charlotte Ling,Peter Kovacs,Erik Ingelsson,Mark I. McCarthy,Alan R. Shuldiner,Kristi D. Silver,Markku Laakso,Leif Groop,Valeriya Lyssenko +63 more
TL;DR: In this paper, the growth factor receptor-bound protein 10 (GRB10) gene was associated with reduced glucose-stimulated insulin secretion and increased risk of type 2 diabetes (T2D) if inherited from the father, but inexplicably reduced fasting glucose when inherited from a mother.