E
Erwin G. Van Meir
Researcher at University of Alabama at Birmingham
Publications - 202
Citations - 39049
Erwin G. Van Meir is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Glioma & Cancer. The author has an hindex of 75, co-authored 183 publications receiving 32866 citations. Previous affiliations of Erwin G. Van Meir include Emory University & University Hospital of Lausanne.
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Journal ArticleDOI
Detection of "Oncometabolite" 2-hydroxyglutarate by Magnetic Resonance Analysis as a Biomarker of IDH1/2 Mutations in Glioma
Juliya Kalinina,Anne Carroll,Liya Wang,Qiqi Yu,Danny E. Mancheno,Shaoxiong Wu,Frank Liu,Jun Ahn,Miao He,Hui Mao,Erwin G. Van Meir +10 more
TL;DR: It is reported that 2HG can be precisely detected by magnetic resonance (MR) in human glioma specimens and used as a reliable biomarker to identify this subset of tumors.
Journal ArticleDOI
Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477))
Cameron Brennan,Roel G.W. Verhaak,Aaron McKenna,Benito Campos,Houtan Noushmehr,Sofie R. Salama,Siyuan Zheng,Debyani Chakravarty,J. Zachary Sanborn,Samuel H. Berman,Rameen Beroukhim,Brady Bernard,Chang-Jiun Wu,Giannicola Genovese,Ilya Shmulevich,Jill S. Barnholtz-Sloan,Lihua Zou,Rahulsimham Vegesna,Sachet A. Shukla,Giovanni Ciriello,W. K. Yung,Wei Zhang,Carrie Sougnez,Tom Mikkelsen,Kenneth Aldape,Darell D. Bigner,Erwin G. Van Meir,Michael D. Prados,Andrew E. Sloan,Keith L. Black,Jennifer M. Eschbacher,Gaetano Finocchiaro,William A. Friedman,David W. Andrews,Abhijit Guha,Mary Iacocca,Brian P. O'Neill,Greg Foltz,Jerome Myers,Daniel J. Weisenberger,Robert Penny,Raju Kucherlapati,Charles M. Perou,D. Neil Hayes,Richard A. Gibbs,Marco A. Marra,Gordon B. Mills,Eric S. Lander,Paul T. Spellman,Rick K. Wilson,Chris Sander,John N. Weinstein,Matthew Meyerson,Stacey Gabriel,Peter W. Laird,David Haussler,Gad Getz,Lynda Chin +57 more
Journal ArticleDOI
Glioma progression is shaped by genetic evolution and microenvironment interactions
Frederick S. Varn,Kevin M. Johnson,Jan Martinek,Jason T. Huse,MacLean Nasrallah,Pieter Wesseling,Lee Cooper,Tathiane M. Malta,Taylor Wade,Thais S. Sabedot,Daniel J. Brat,Peter Gould,Adelheid Wöehrer,Kenneth Aldape,Azzam Ismail,Santhosh Sivajothi,Floris P. Barthel,Hoon-Kyo Kim,Emre Kocakavuk,Nazia Ahmed,Kieron White,Indrani Datta,Hyo Eun Moon,Steven Pollock,Christine N. Goldfarb,Ga Hyun Lee,Luciano Garofano,Kevin W. Anderson,Djamel Nehar-Belaid,Jill S. Barnholtz-Sloan,Spyridon Bakas,Annette T. Byrne,Fulvio D'Angelo,Hui K Gan,Mustafa Khasraw,Simona Migliozzi,D. Ryan Ormond,Sun Ha Paek,Erwin G. Van Meir,Annemiek M E Walenkamp,Colin Watts,Tobias Weiss,Michael Weller,A. Karolina Palucka,Lucy F. Stead,Laila M. Poisson,Houtan Noushmehr,Antonio Iavarone,Roel G.W. Verhaak,Kristin Alfaro,Samirkumar B. Amin,David M. Ashley,Christoph Bock,Andrew Brodbelt,Ketan R. Bulsara,Ana Valeria B Castro,Jennifer Connelly,Joseph F. Costello,John de Groot,G. Finocchiaro,Pim J. French,Anna Golebiewska,Annika Hau,Chibo Hong,Craig Horbinski,Kasthuri Kannan,Mathilde C.M. Kouwenhoven,Anna Lasorella,Peter S. LaViolette,Keith L. Ligon,Allison Lowman,Shwetal Vatsal Mehta,Hrvoje Miletic,Annette M. Molinaro,Ho Keung Ng,Simone P. Niclou,Johanna M. Niers,T. J. Phillips,Raul Rabadan,Ganesh Rao,Guido Reifenberger,Nader Sanai,Susan C Short,Peter A. E. Sillevis Smitt,Andrew E. Sloan,Marion Smits,James M. Snyder,Hiromichi Suzuki,Ghazaleh Tabatabai,Georgette Tanner,William H. Tomaszewski,Michael J. Wells,Bart A. Westerman,Helen Wheeler,Jichun Xie,W. K. Alfred Yung,Gelareh Zadeh,Junfei Zhao +97 more
TL;DR: In this paper , RNA and/or DNA sequencing data from the temporally separated tumor pairs of 304 adult patients with isocitrate dehydrogenase (IDH)-wild-type and IDH-mutant glioma were analyzed.
Journal ArticleDOI
Cytokines and tumors of the central nervous system.
TL;DR: A variety of cytokines are expressed during CNS neoplasia; their potential involvement in tumor growth through a variety of mechanisms, such as autocrine or paracrine growth stimulation, angiogenesis, and immune surveillance evasion, are discussed.
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PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion.
TL;DR: It is demonstrated that PIKE-A is a physiologic regulator of Akt and an oncogenic effector of cell invasion, whereas dominant-negative PIke-A and PIK-A knockdown markedly inhibit these processes.