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Erwin G. Van Meir

Researcher at University of Alabama at Birmingham

Publications -  202
Citations -  39049

Erwin G. Van Meir is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Glioma & Cancer. The author has an hindex of 75, co-authored 183 publications receiving 32866 citations. Previous affiliations of Erwin G. Van Meir include Emory University & University Hospital of Lausanne.

Papers
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The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis

TL;DR: A precise definition of the mechanisms by which IL-8 exerts its proangiogenic functions requires further study for the development of effectiveIL-8-targeted therapies.
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Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Alison M. Taylor, +732 more
- 09 Apr 2018 - 
TL;DR: The genomic and phenotypic correlates of cancer aneuploidy are defined and genome engineering is applied to delete 3p in lung cells, causing decreased proliferation rescued in part by chromosome 3 duplication.
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Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

TL;DR: Hypoxia-inducible factor 1 (HIF-1) is a critical regulatory factor in the tumor microenvironment because of its central role in promoting proangiogenic and invasive properties.
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Natural mutagenesis of human genomes by endogenous retrotransposons.

TL;DR: The data indicate that transposon-mediated mutagenesis is extensive in human genomes and is likely to have a major impact on human biology and diseases.
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'Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis

TL;DR: Vaso-occlusive and prothrombotic mechanisms in GBM could readily explain the presence of pseudopalisading necrosis in tissue sections, the rapid peripheral expansion on neuroimaging, and the dramatic shift to an accelerated rate of clinical progression resulting from hypoxia-induced angiogenesis.