Fergus Shanahan

TL;DR: A group of international experts appointed by the World Gastroenterology Organization prepared a practical guideline on the current indications of probiotics and prebiotics in GastroEnterology, which underscores strain-specificity of the clinical effects, and provides precise information on which specific probiotic strains or prebiotic compounds are useful for what particular clinical indications.

TL;DR: It is shown that the cyclooxygenase (COX) signalling pathway, and in particular prostaglandin E2 (PGE2), plays a role in the upregulation of FasL expression in colon cancer, adding another pro-neoplastic activity to PGE2.

TL;DR: It is concluded that canine fundic mast cells possess receptors for immunoglobulin E and adenosine, consistent with increases in cytosolic calcium and protein kinase C activation working synergistically to stimulate fundicmast cells.

TL;DR: Clinification of the molecular basis of host-microbe interactions in health and in susceptible individuals promises novel therapeutic strategies.

TL;DR: Results would suggest that rectal administration of thuricin may be a promising mode of delivery of thURicin CD to the colon.