F
Fergus Shanahan
Researcher at National University of Ireland
Publications - 727
Citations - 59181
Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.
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Journal ArticleDOI
Intranasal Bifidobacterium longum protects against viral-induced lung inflammation and injury in a murine model of lethal influenza infection.
David Groeger,Elisa Schiavi,Ray Grant,Magdalena Kurnik-Łucka,David Michalovich,Rick Williamson,Soren Beinke,Barry Kiely,Cezmi A. Akdis,Edith M. Hessel,Fergus Shanahan,Liam O’ Mahony +11 more
TL;DR: Exposure to these bifidobacterium longum strains protect against the inflammatory sequelae and damage associated with uncontrolled viral replication within the lung.
Journal ArticleDOI
Modelling the Major Histocompatibility Complex Susceptibility to RA Using the MASC Method
Emmanuelle Génin,Marie-Claude Babron,Michael F. McDermott,B. Mulcahy,F. Waldron-Lynch,Claire Adams,Daniel O. Clegg,Ryk Ward,Fergus Shanahan,M. G. Molloy,Fergal O'Gara,Françoise Clerget-Darpoux +11 more
TL;DR: The TNF data provided additional information for a better understanding of genetic susceptibility to RA than was previously possible using only HLA‐DR data and the advisability of using different linked markers in a candidate region for modelling the contribution of this region in disease susceptibility is addressed.
Journal ArticleDOI
The gut virome in Irritable Bowel Syndrome differs from that of controls.
TL;DR: The most common cause of Irritable Bowel Syndrome (IBS), the most common gastrointestinal disorder, is diagnosed solely on symptoms as discussed by the authors, and diagnostic alterations in the bacterial component of the gut microbiome (the...
Journal ArticleDOI
Gut microbiota: implications for sports and exercise medicine
Owen Cronin,Owen Cronin,Orla O'Sullivan,Orla O'Sullivan,Wiley Barton,Paul D. Cotter,Paul D. Cotter,Michael G. Molloy,Michael G. Molloy,Fergus Shanahan,Fergus Shanahan +10 more
TL;DR: The gut microbiota, the trillions of microbes including bacteria, viruses and fungi, which reside within the gut, are now recognised as significant contributors to human (host) health.
Journal ArticleDOI
Preparation of a standardised faecal slurry for ex-vivo microbiota studies which reduces inter-individual donor bias
Michelle M. O'Donnell,Michelle M. O'Donnell,Mary C. Rea,Mary C. Rea,Orla O'Sullivan,Orla O'Sullivan,Cal Flynn,Beth Jones,Albert McQuaid,Fergus Shanahan,R. Paul Ross,R. Paul Ross +11 more
TL;DR: This study provides a method to produce a standardised human faecal inoculum suitable for freezing by lessening the effect of inter-individual variation among the donors, thereby making the system more suitable for the accurate interpretation of the effects of experimental treatments.