F
Fergus Shanahan
Researcher at National University of Ireland
Publications - 727
Citations - 59181
Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.
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Journal ArticleDOI
Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation
Triona Goode,J. O'Connell,Peter A. Anton,Helen Wong,Joseph R. Reeve,G C O'Sullivan,J.K. Collins,Fergus Shanahan +7 more
TL;DR: This report demonstrates the strategic localisation and upregulation of NK-1R expression in IBD colon, and thereby suggests the involvement of substance P in the pathophysiological symptoms of IBD.
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Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors.
Timothy G. Dinan,Gerard Clarke,Eamonn Martin Quigley,Lucinda V. Scott,Fergus Shanahan,John F. Cryan,J. M. Cooney,P. W. N. Keeling +7 more
TL;DR: IBS and major depression are characterized by a pro-inflammatory profile, whereas IBS patients alone exhibit an exaggerated muscarinic receptor-mediated IL-6 response.
Journal Article
Physicians' perceptions of dysplasia and approaches to surveillance colonoscopy in ulcerative colitis
TL;DR: Dysplasia surveillance colonoscopy in ulcerative colitis is not a well standardized, clearly understood screening tool, and continued education of the gastroenterology community regarding its outcomes and pitfalls is needed.
Journal ArticleDOI
Exercise and the microbiota
Orla O'Sullivan,Owen Cronin,Siobhan F. Clarke,Eileen F. Murphy,M. G. Molloy,Fergus Shanahan,Paul D. Cotter +6 more
TL;DR: The relationship between extreme levels of exercise, associated dietary habits and gut microbiota composition are assessed, and potential mechanisms by which exercise may exert a direct or indirect influence on gut microbiota are discussed.
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Sulfate-reducing bacteria colonize pouches formed for ulcerative colitis but not for familial adenomatous polyposis.
Duffy M,Liam O'Mahony,John Calvin Coffey,Collins Jk,Fergus Shanahan,Henry Paul Redmond,William O. Kirwan +6 more
TL;DR: Ileal pouch-anal anastomosis remains the “gold standard” in surgical treatment of ulcerative colitis and familial adenomatous polyposis and sulfate-reducing bacteria are exclusive to patients with a background of ulcersated colitis.